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Wednesday 09 February 2022 20:20:32 GMT
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Your period blood is powerful enough to help repair a damaged heart 🫀 When a heart attack weakens the heart, it can't pump blood properly 💔 Scientists tested two cell types head to head 🔬 🦴 Gold standard: bone marrow stem cells 🩸 Menstrual stem cells (MenSCs) 💓 They don't just help — they can become heart muscle A 2008 study found MenSCs can be grown into beating, functioning heart cells in the lab — 27-32% converted, with real heart-like electrical activity. An even more potent version, cells from detached uterine lining fragments in the same blood, converted at 76-97%. Bone marrow stem cells only managed 0.3%. Transplanted into rats with heart attacks, MenSCs wove into the damaged heart tissue within two weeks, matching real heart muscle's striped structure - restoring more pumping power and shrinking infarct size more than bone marrow cells. When a heart attack happens, there is a cascade of events: ➡️ Blood backs up, pressure rises ➡️ Fluid floods the lungs 🫁💧 ➡️ Inflammation starts destroying lung cells 🫁 They protect the lungs too In a 2026 study, MenSCs outperformed bone marrow cells on lung cell death and inflammation, and were the only ones to suppress a key inflammatory pathway (NF-κB → iNOS). Both cell types reduced lung scarring by a similar amount. 🧫 Why MenSCs might be the more practical option Easier to collect (no invasive harvesting), faster to proliferate, and able to expand for 20+ passages without genetic abnormalities. ⚠️ Promising mechanistic data, but a long way from human treatment. Menstrual blood-derived cell therapy is still an emerging field. Hida et al. Novel cardiac precursor-like cells from human menstrual blood-derived mesenchymal cells. Stem Cells. 2008 Manshori et al. Menstrual blood-derived stromal cells exhibit superior protection against lung injury in myocardial infarction-induced heart failure in rats compared to bone marrow-derived stromal cells. Regen Ther. 2026 #menstrualstemcells #periodblood #stemcells #heartattack #WomenInScience
Your period blood is powerful enough to help repair a damaged heart 🫀 When a heart attack weakens the heart, it can't pump blood properly 💔 Scientists tested two cell types head to head 🔬 🦴 Gold standard: bone marrow stem cells 🩸 Menstrual stem cells (MenSCs) 💓 They don't just help — they can become heart muscle A 2008 study found MenSCs can be grown into beating, functioning heart cells in the lab — 27-32% converted, with real heart-like electrical activity. An even more potent version, cells from detached uterine lining fragments in the same blood, converted at 76-97%. Bone marrow stem cells only managed 0.3%. Transplanted into rats with heart attacks, MenSCs wove into the damaged heart tissue within two weeks, matching real heart muscle's striped structure - restoring more pumping power and shrinking infarct size more than bone marrow cells. When a heart attack happens, there is a cascade of events: ➡️ Blood backs up, pressure rises ➡️ Fluid floods the lungs 🫁💧 ➡️ Inflammation starts destroying lung cells 🫁 They protect the lungs too In a 2026 study, MenSCs outperformed bone marrow cells on lung cell death and inflammation, and were the only ones to suppress a key inflammatory pathway (NF-κB → iNOS). Both cell types reduced lung scarring by a similar amount. 🧫 Why MenSCs might be the more practical option Easier to collect (no invasive harvesting), faster to proliferate, and able to expand for 20+ passages without genetic abnormalities. ⚠️ Promising mechanistic data, but a long way from human treatment. Menstrual blood-derived cell therapy is still an emerging field. Hida et al. Novel cardiac precursor-like cells from human menstrual blood-derived mesenchymal cells. Stem Cells. 2008 Manshori et al. Menstrual blood-derived stromal cells exhibit superior protection against lung injury in myocardial infarction-induced heart failure in rats compared to bone marrow-derived stromal cells. Regen Ther. 2026 #menstrualstemcells #periodblood #stemcells #heartattack #WomenInScience

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