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@thegirldadlife: first time holding a frog and her nervous laughter. #frog #wildlife #wi #usa #viral #fyp #grass #crocs
The Girl Dad Life
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Region: US
Wednesday 09 August 2023 00:50:29 GMT
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Researchers are investigating connections between mast cell activation, histamine dysregulation, and neurodivergent conditions. Mast cells are immune cells that release histamine, cytokines, and other inflammatory mediators. They surround the blood brain barrier and can influence neuroinflammation. Multiple studies suggest overlap between Mast Cell Activation Syndrome (MCAS), ADHD, autism, anxiety, endometriosis, POTS, EDS, and chronic allergic conditions. A 2020 review in Experimental and Therapeutic Medicine proposed mast cell-mediated neuroinflammation may contribute to ADHD. A 2025 review in Neuroscience and Biobehavioral Reviews explored mast cell involvement in autism spectrum disorder through neuroinflammation and gut-brain axis disruption. Important caveat: this research is still emerging. Most findings are correlational rather than causal. Do not self diagnose MCAS. If symptoms resonate, find a doctor familiar with mast cell disorders. Sources: Aitella et al. 2026, Biomolecules: https://www.mdpi.com/2218-273X/16/4/530 Weinstock et al. 2025, prevalence of neuropsychiatric symptoms in MCAS: https://pmc.ncbi.nlm.nih.gov/articles/PMC12270938/ Song et al. 2020, mast cells and ADHD neuroinflammation #mcas #adhd #autism #chronicillness #wellness
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