@melanin_goddess2023: New Challenge song of the year,Make a short video of you posing to the Camera.Tag our page and we will help promote it. #CurvyElegance #BlackGirlMagic #GorgeousQueen #BlackIsBeautiful #EbonyPrincess #RoyalInHerOwnRight #confidentlybeautiful #EbonyPrincess #RoyalInHerOwnRight #confidentlybeautiful #MelaninQueen #GlowingWithPride #BlackQueen #CrownedInExcellence #Royalty #blackqueen #UnstoppableQueens #blackqueens #blacklove #celebratediversity #MelaninMagic #ExcellenceUnleashed #BlackGirlMotivation #brightfuture #bright #body #bodygoal #smash #eyesoff #attractivebody #trending #trendingvideos #billionviews #viral #worldwide #usa #unitedkingdom #australia #africa

MelaninGoddess
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Friday 03 May 2024 01:22:13 GMT
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These videos are taken from one of my favorite papers published in 2021 in the journal Developmental Cell entitled:
These videos are taken from one of my favorite papers published in 2021 in the journal Developmental Cell entitled: "3D mesenchymal cell migration is driven by anterior cellular contraction that generates an extracellular matrix prestrain" by one of my absolute favorite scientist Professor Kenneth Yamada from the National Institute of Health in Bethesda. This paper captivates me firstly because of its absolutely stunning microscopy images. The scientists fluorescently labeled both the cells and the collagen fibers and then use a confocal microscope to observe. The paper studies how cells generate forces when migrating in a 3D environment, which is often the case for a cell inside a body. The main model the study used is human fibroblast. They found that in a 3D collagen matrix, the same protein found in your skin, cells create these front bundled-up collagen as they move. They use integrins (remember integrins that I introduce to you a few posts back?) to grab on to these fibers, and essentially pull them together to help the cell move forward. It is like an acrobat trying to move from one string of rope to another. When they use lasers to cut these fibers at the front, the cells lost their anchors and retract. It turns out, many cancer cells can use the same mechanism to move around. And we can inhibit this grabbing mechanism or even change the mechanical properties of the surrounding environment, and this can halt the migration and potentially the spread of cancer cells to distant organs. This study shows that the mechanical properties of the environment can have an impact on how cells behave, or more specifically how cancer cells behave. So perhaps, if you're a material scientist seeing this post, maybe this will trigger your curiosity? #cancer #biology #cell #3D #collagen #Science #scientist #medicine #phd #stem #tiktok #fyp

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