@mindset_usmle: A simplified non-PhD explanation of how Adderall works is that it enhances focus by blocking dopamine (DAT) and norepinephrine (NET) transporters, preventing reuptake and increasing their levels in the synapse. It actually REVERSES transporter function and promotes the release of more neurotransmitters from vesicles, amplifying its effects. For USMLE Step 1, understanding Adderall’s mechanism involves knowing how amphetamines increase catecholamine activity in the central nervous system, particularly in the prefrontal cortex for attention regulation and the nucleus accumbens for reward processing. For USMLE Step 2, its clinical applications go beyond ADHD, as it is also used to treat narcolepsy by increasing wakefulness and, in some cases, treatment-resistant depression due to its stimulant effects on motivation and mood. Additionally, it can be used off-label for binge-eating disorder to reduce compulsive eating behaviors. Follow us for more med school tips and good luck! :) #USMLE #USMLEPrep #USMLEStep1 #USMLEStep2 #USMLETips #Step1Prep #Step2CK #Step3 #NBME #UWorld #MedStudent #MedStudentLife #Doctor #MedicalSchool #MedicalMeme #MemePage #Meme #PhysicianAssistant #Medicine #StudyMotivation #StudyTips #NursingSchool #StudyGoals #Anki #MedEd #Flashcards #StudySmart #StudyWithMe #MedicalEducation #Premed

Mindset USMLE

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Tuesday 25 February 2025 22:36:45 GMT