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𝑅สɓɓ𝙮
𝑅สɓɓ𝙮
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Friday 19 September 2025 02:16:06 GMT
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mdismail528000
ইসমাইল ভাই 🤗 :
চাঁদের চেয়েও বেশি সুন্দর আমাদের নবীজি😊
2025-09-20 04:42:48
594
jannatalirashtom
🦋Mariya Islam 🦋 :
ভাই এতো সুন্দর গান আগে সুনি নাই 🙂☹
2025-09-19 11:09:26
1541
tamim25335
Tamim :
ভাইয়াএটাকোথায়😁😁😁😁😁😁😁😁😁😁🫣🫣🫣🫣🫣🫣🫣🫣🫣
2025-09-24 17:05:03
0
nila.akter7720
🌿🥀-ব্যর্থ জীবন-🥀🌿 :
গানের নাম কি 😩🤭
2025-09-20 04:07:49
42
ratri.mondal28
Romantic Girl😅🥀 :
এই যে আইছে ছ্যাচড়া কমেন্ট পড়তে 🔪🚬
2025-09-20 01:53:26
147
eshrat2434
~TꫝniSꫝ♡ :
Gf নেই এমন ছেলে পৃথিবীতে নেই ....🙂👍
2025-09-22 05:56:31
13
pakhe2244
Shakha.. 🥀❤️‍🩹 :
দারা দারা তোরা একা পারবি না আমি আসছি মাঠে 😆😆😆😆😆😆
2025-09-19 11:59:11
416
tulymone2
Albida 💔💔 :
কে কে জীবনে এক বার হোলেও মাঠে এরোকোম করে ফুটবল খেলেছো 🤣🤣🤣
2025-09-24 13:00:00
0
sorna.akter5112
🦋🥀SORNA@AKTER🐝🦋🐚 :
তাই বলে এই সাউন্ড দিবেন🤣🥴
2025-09-20 19:29:00
45
adibatanzim
Adiba Tanzim💗 :
ভিডিও টার সাথে গানের অনেক মিল আছে 😅😅😅😅😁😁😁
2025-09-24 03:27:47
17
hafsaislam0298
🤭জাতির ভন্ড আপা 🤭 :
এটা কী গান ভাইয়া
2025-09-19 12:32:12
97
no__love_tanya0
🇧🇷মায়াবতী🇧🇷 :
🤔কেউ কি আমার সাথে প্রেম করবে🤘💔🇧
2025-09-20 06:47:13
15
queen..mim09
᪣ℚ𝕦𝕖𝕖𝕟.𝕄𝕚𝕄᪣ :
ঔ কেউ প্রেম করবা💐💐
2025-09-20 03:41:52
11
keshavati.daughter
Keshavati daughter 🌸 :
এইখানে আমিও আছি 🥲
2025-09-20 08:33:32
15
mdjihad0137
🥀🥀💔Sumaiya💔🥀🥀 :
এতো বড় সমান 😁😁😁
2025-09-20 01:11:13
111
babu.golam
Md Jamil :
খুব সুন্দর
2025-09-25 02:47:12
0
mim9392613686215
🍂🍁দুঃখবতী🍁🍂 :
ki bole😂
2025-09-19 02:28:31
6
mstsonia246
─🍒͟͟͞͞তোঁমাঁগোঁ ভাঁবিঁ লাঁগিঁ :
ও মায়া মায়া গো মিলছে 🤣🤣🤣
2025-09-19 13:50:30
35
rj_rocky8
Rocky :
গোল কি হবে আজও😀
2025-09-19 09:45:33
34
___ahad__007___
AHAD>3❤️‍🩹 :
গানের নাম ✅🫵🫵
2025-09-19 17:36:45
11
tiktok.com928m
🎀it's me zara🎀 :
কি একটা অবস্থা 🤭🤭
2025-09-19 06:00:32
12
riya33341
🌸 রুপবতী 🌸 :
o.ma.go..amader scl dekhi vairal hoye gese 😳😫
2025-09-20 15:35:48
5
tamanna.akther787
Tamanna Akther :
ভাইরাল হইয়া গেলে তুমি 😳🙄
2025-09-20 10:25:27
3
mst.laboni8864
Mst Sadiya :
দেখ বান্ধবী তোরা ভাইরাল হয়া গেছু 😂😂😂
2025-09-23 06:17:23
4
nusrat.jahan.mim3780
🌸🦋 Nusrat Jahan Mim 🕊️🌷 :
আমি এক জাউরা..!! 🙂👍 আমার কমেন্ট যে পরতাছে সে আরেক জাউড়া..!!🐸🤌🏼😒
2025-09-22 14:03:04
9
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1. Both are biogenic amines Histamine → from histidine (needs DAO/HNMT to break down). Serotonin → from tryptophan (needs vitamin B6 + cofactors). Both are cleared in the gut and liver → if one pathway is overloaded, the other can be affected. Gut Connection 90% of serotonin is made in the gut. Histamine in the gut (from food or bacteria) can stimulate serotonin release → leading to IBS-like symptoms (diarrhea, cramping, nausea). This is why some with histamine intolerance also struggle with serotonin-related gut issues. Mood & Brain Effects Histamine in the brain is stimulating (wakefulness, alertness). Serotonin is more calming/stabilizing (mood, sleep). Too much histamine → anxiety, insomnia, racing thoughts. Low serotonin + high histamine → irritability, low mood, “tired but wired. Oestrogen raises both histamine and serotonin activity (why mood swings + histamine flares can worsen mid-cycle or in PMS). Progesterone balances both by calming mast cells (↓ histamine) and supporting GABA (calming neurotransmitter). Nutrient & Enzyme Crossroads Both serotonin and histamine need methylation (SAMe, folate, B12, magnesium) for breakdown. If methylation is sluggish, you can get high histamine + low serotonin, or the opposite depending on diet/genetics. If you have high histamine + anxiety/insomnia, calming serotonin support may help (tryptophan foods, B6, magnesium, gut support). If you have low mood + histamine intolerance, be careful: serotonin precursors (tryptophan, 5-HTP) can worsen histamine symptoms because they share breakdown pathways. Balance is key: support gut health, ensure B6/folate/B12/magnesium are adequate, and manage oestrogen swings.
1. Both are biogenic amines Histamine → from histidine (needs DAO/HNMT to break down). Serotonin → from tryptophan (needs vitamin B6 + cofactors). Both are cleared in the gut and liver → if one pathway is overloaded, the other can be affected. Gut Connection 90% of serotonin is made in the gut. Histamine in the gut (from food or bacteria) can stimulate serotonin release → leading to IBS-like symptoms (diarrhea, cramping, nausea). This is why some with histamine intolerance also struggle with serotonin-related gut issues. Mood & Brain Effects Histamine in the brain is stimulating (wakefulness, alertness). Serotonin is more calming/stabilizing (mood, sleep). Too much histamine → anxiety, insomnia, racing thoughts. Low serotonin + high histamine → irritability, low mood, “tired but wired. Oestrogen raises both histamine and serotonin activity (why mood swings + histamine flares can worsen mid-cycle or in PMS). Progesterone balances both by calming mast cells (↓ histamine) and supporting GABA (calming neurotransmitter). Nutrient & Enzyme Crossroads Both serotonin and histamine need methylation (SAMe, folate, B12, magnesium) for breakdown. If methylation is sluggish, you can get high histamine + low serotonin, or the opposite depending on diet/genetics. If you have high histamine + anxiety/insomnia, calming serotonin support may help (tryptophan foods, B6, magnesium, gut support). If you have low mood + histamine intolerance, be careful: serotonin precursors (tryptophan, 5-HTP) can worsen histamine symptoms because they share breakdown pathways. Balance is key: support gut health, ensure B6/folate/B12/magnesium are adequate, and manage oestrogen swings.
🔹 Main Causes of High Histamine Overproduction of Histamine Mast cell activation (Mast Cell Activation Syndrome / MCAS) → mast cells release too much histamine. Chronic infections (EBV, Lyme, Candida, parasites, SIBO) → stimulate immune cells to release histamine. Allergies / atopy → pollen, dust, mold, food allergies. Hormonal influences → high oestrogen stimulates mast cells to release more histamine (common around ovulation, PMS, perimenopause). Stress → high cortisol and adrenaline can trigger mast cell degranulation. Reduced Breakdown of Histamine Histamine is cleared by two main enzymes: DAO (Diamine Oxidase) → works in the gut, breaks down histamine from food. HNMT (Histamine N-Methyltransferase) → works inside cells, especially in the brain and liver. Causes of reduced breakdown: DAO deficiency (genetic variants, gut inflammation, nutrient deficiencies). Medications that block DAO (NSAIDs, some antidepressants, antihypertensives). Nutrient deficiencies needed for DAO/HNMT → Vitamin B6, Copper, Vitamin C, SAMe, Folate. Gut damage → IBS, IBD, leaky gut, celiac, or SIBO can lower DAO production. Liver dysfunction → slows HNMT activity. Dietary & Lifestyle Sources High-histamine foods: aged cheese, smoked/processed meats, fermented foods, alcohol, vinegar, leftovers. Histamine liberators (not high in histamine themselves, but trigger release): citrus, strawberries, tomatoes, chocolate, shellfish. Alcohol → blocks DAO and increases histamine release. Poor sleep / circadian disruption → histamine is part of the wake-sleep cycle. What High Histamine Feels Like Headaches or migraines Flushing, hives, itching Runny nose, sinus congestion Heart palpitations, dizziness Anxiety, insomnia, restlessness PMS or heavy, painful periods Digestive upset: bloating, diarrhea, cramping.
🔹 Main Causes of High Histamine Overproduction of Histamine Mast cell activation (Mast Cell Activation Syndrome / MCAS) → mast cells release too much histamine. Chronic infections (EBV, Lyme, Candida, parasites, SIBO) → stimulate immune cells to release histamine. Allergies / atopy → pollen, dust, mold, food allergies. Hormonal influences → high oestrogen stimulates mast cells to release more histamine (common around ovulation, PMS, perimenopause). Stress → high cortisol and adrenaline can trigger mast cell degranulation. Reduced Breakdown of Histamine Histamine is cleared by two main enzymes: DAO (Diamine Oxidase) → works in the gut, breaks down histamine from food. HNMT (Histamine N-Methyltransferase) → works inside cells, especially in the brain and liver. Causes of reduced breakdown: DAO deficiency (genetic variants, gut inflammation, nutrient deficiencies). Medications that block DAO (NSAIDs, some antidepressants, antihypertensives). Nutrient deficiencies needed for DAO/HNMT → Vitamin B6, Copper, Vitamin C, SAMe, Folate. Gut damage → IBS, IBD, leaky gut, celiac, or SIBO can lower DAO production. Liver dysfunction → slows HNMT activity. Dietary & Lifestyle Sources High-histamine foods: aged cheese, smoked/processed meats, fermented foods, alcohol, vinegar, leftovers. Histamine liberators (not high in histamine themselves, but trigger release): citrus, strawberries, tomatoes, chocolate, shellfish. Alcohol → blocks DAO and increases histamine release. Poor sleep / circadian disruption → histamine is part of the wake-sleep cycle. What High Histamine Feels Like Headaches or migraines Flushing, hives, itching Runny nose, sinus congestion Heart palpitations, dizziness Anxiety, insomnia, restlessness PMS or heavy, painful periods Digestive upset: bloating, diarrhea, cramping.

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