@instituteofhumananatomy: PART 2: The Cellular Truth About Skin Color (It's Not What You Think) Zooming into that paper-thin epidermis to understand what's actually happening at the cellular level. THE CELL BREAKDOWN: 90% of epidermal cells are keratinocytes - they produce keratin for protection and bind cells together 8% are melanocytes - they produce melanin (the pigment) THE LAYERS: Stratum basale (bottom layer): Single row of constantly dividing keratinocytes with melanocytes interspersed Stratum spinosum (above): 8-10 cell layers thick where melanocytes also deposit pigment HERE'S THE SHOCKING PART: Everyone has roughly the same number of melanocytes regardless of skin tone. Light skin, dark skin - about 8% of your epidermal cells are melanocytes. The difference? Activity level and melanin production at baseline. HOW IT WORKS: Each melanocyte has cytoplasmic extensions (like little arms) that contact up to 30 keratinocytes. They deposit melanin into these cells, giving them color. More melanin = darker pigmentation. TANNING EXPLAINED: UV exposure stimulates melanocytes to produce MORE melanin, protecting DNA from damage. This is why darker-skinned individuals have better natural protection against skin cancer. When you stop getting sun exposure, those darker keratinocytes eventually flake off and new, lighter ones replace them. Want to maintain a tan? You need constant UV stimulation. THE PROTECTIVE MECHANISM: Melanin shields the nucleus and DNA inside keratinocytes from UV damage and potential mutations. It's your body's natural sunscreen. Coming up in Part 3: Why palm pigmentation differs and the sun damage connection. Visit the link in our bio for 60% off our "Understanding Skin" eBook! #Melanocytes #Keratinocytes #SkinPigmentation #Melanin #UVProtection #Epidermis #Tanning #SkinScience

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Thursday 02 October 2025 00:00:00 GMT
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ejc1984
Eric_Colmark :
Fascinating. Is damaged dna, and potentially gene mutation, of the keratinocytes a contributing factor to basal cell carcinoma?
2025-10-02 03:14:40
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yesisantos00
Yesi Santos :
Thank you for this it was very helpful!!
2026-02-27 15:23:37
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fred_d726
Fred_D :
was that skin?
2025-11-04 20:18:52
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user2569018222224
user256901822222416.15Bermerre :
[email protected]:@user256901822222416.15Bermerre:Error 400 (Bad Request)!!1user842113337885946
2025-10-02 02:07:31
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