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Friday 10 October 2025 12:06:22 GMT
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Naked mole rats almost never get cancer. And the reason why might have something to do with a molecule your body already makes. In this conversation with Dr. Vera Gorbunova and Dr. Andrei Seluanov, they break down one of the more fascinating findings in longevity research: the role of hyaluronic acid. Your body produces it. But the naked mole rat produces a version that's six to ten times longer. That difference in length changes how the tissue behaves — it becomes more elastic, holds water better, and appears to create an environment where cancer simply can't take hold. When they tried to intentionally grow a tumor from naked mole rat cells in a petri dish, they couldn't do it. But the moment they blocked those cells from producing hyaluronic acid, tumor growth became possible. That finding pointed to something bigger. So they engineered a mouse to carry the gene responsible for producing this longer form of hyaluronic acid. The result: less cancer, and a lifespan extended by roughly ten to fifteen percent. A molecule your body already makes — just not quite like this. Tune into the full conversation, out now on all major streaming platforms.
Naked mole rats almost never get cancer. And the reason why might have something to do with a molecule your body already makes. In this conversation with Dr. Vera Gorbunova and Dr. Andrei Seluanov, they break down one of the more fascinating findings in longevity research: the role of hyaluronic acid. Your body produces it. But the naked mole rat produces a version that's six to ten times longer. That difference in length changes how the tissue behaves — it becomes more elastic, holds water better, and appears to create an environment where cancer simply can't take hold. When they tried to intentionally grow a tumor from naked mole rat cells in a petri dish, they couldn't do it. But the moment they blocked those cells from producing hyaluronic acid, tumor growth became possible. That finding pointed to something bigger. So they engineered a mouse to carry the gene responsible for producing this longer form of hyaluronic acid. The result: less cancer, and a lifespan extended by roughly ten to fifteen percent. A molecule your body already makes — just not quite like this. Tune into the full conversation, out now on all major streaming platforms.

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