@profahmedhankir: Methadone is a life-saving treatment for opioid use disorder. Taken as a daily oral liquid, it occupies opioid receptors long-term — reducing cravings, preventing withdrawal, and meaning that using heroin on top usually doesn’t produce the same euphoric effect. Because it’s taken orally, methadone also reduces injecting, lowering the risk of HIV and hepatitis C. It isn’t about replacing one addiction with another. It’s about harm reduction, stability, and dignity. If you or someone you care about is struggling, evidence-based treatment works — and methadone is one of the most studied and effective options we have. #addictions #MentalHealth #psychiatry 1. World Health Organization (WHO) Guidelines for the Psychosocially Assisted Pharmacological Treatment of Opioid Dependence WHO, Geneva. – Confirms methadone as an effective opioid agonist therapy that reduces illicit opioid use, overdose risk, and transmission of blood-borne viruses. 2. National Institute for Health and Care Excellence (NICE) NG46: Drug misuse in over 16s – opioid detoxification and maintenance NICE, UK. – Recommends methadone as first-line opioid substitution therapy; supports supervised dosing and oral administration. 3. Cochrane Database of Systematic Reviews Mattick RP et al. Methadone maintenance therapy versus no opioid replacement therapy for opioid dependence Cochrane Review. – Demonstrates improved treatment retention and reduced heroin use with methadone maintenance. 4. The Lancet Degenhardt L et al. The impact of opioid substitution therapy on mortality among people with opioid dependence The Lancet. – Shows significant reductions in all-cause and overdose mortality during methadone treatment. 5. Substance Abuse and Mental Health Services Administration (SAMHSA) Medications for Opioid Use Disorder (TIP 63) U.S. Department of Health and Human Services. – Details mechanism, dosing, safety considerations, and public-health benefits of methadone.

Professor Ahmed Hankir

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Friday 19 December 2025 15:33:17 GMT