@tilscience: Today I Learned that before fridges, people put live FROGS in their milk. For centuries, Russian and Finnish communities dropped brown frogs (Rana temporaria) into milk vessels to keep them fresh longer. It worked, they just didn’t know why. Fast forward to 2012: Scientists at Moscow State University discovered the frog’s skin secretes a cocktail of antimicrobial peptides (like Brevinin 1Tb) that fight off bacteria like Staphylococcus and Salmonella. Nature’s preservative. Now researchers are exploring whether frog skin compounds could be used to develop new antibiotics. Study: Composition and Antimicrobial Activity of the Skin Peptidome of Russian Brown Frog Rana temporaria T. Yu. Samgina, E. A Vorontsov, V. A. Gorshkov, E. Hakalehto, O. Hanninen, R. A. Zubarev, and A. T. Lebedev Journal of Proteome Research 2012 11 (12), 6213-6222 DOI: 10.1021/pr300890m #Science #antibiotics #microbiologywes #medicine #todayilearned

Dr. Harini Bhat, PharmD
Dr. Harini Bhat, PharmD
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Tuesday 30 December 2025 18:11:01 GMT
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tiktorpjk45
Joe :
As a biologist, I’ve often wondered how people initially thought of stuff like this before understanding the microbial world. Did they just start dropping random things in the milk or did a frog just happen to accidentally get in the milk?
2025-12-30 18:26:03
3951
pi2497i
P :
Ok but isn’t the frog 💩ing in there?
2025-12-30 18:31:52
1391
weedpro
weedpro :
dont let the raw milk people see this
2025-12-30 20:54:14
1110
dont.give.up.keep.growin
Legally Human,Emotionally Cat :
Modern Mom: Did you remember to take the chicken out the freezer to thaw? 1900s Mom: Did you remember to put the frog in the milk?
2025-12-30 21:58:17
1171
curioussunshine
Sarah :
I think we are giving humans too much credit, clearly it was the frogs original idea and we humans just noticed that the milk that the frog got into lasted longer 😆
2025-12-30 23:40:24
196
village.witch.333
ViLLAGE.WiTCH.333 :
How did humans survive all these years lol
2025-12-31 12:53:29
46
nadiadandachi
Nadia Dandachi :
Does the frog stay there? Does it die inside? Or is it taken out quickly? I have so many questions 😂
2025-12-30 20:44:59
108
ryleeeeee90
Ryleeeeee90 :
yeah but who was the first person to do that and figure out it worked? haha
2025-12-30 18:31:41
150
30somethingsomething
Dr. Kim | New View on Healing :
Oh lordt. The “raw milk” people gonna see this and start frogging their milk.
2025-12-31 05:02:23
9
jollijojo88
ᆞֆʊʍʍɛʀᆞ 🇨🇦 :
2025-12-31 04:45:10
10
shh.dont.tell.mum
Mishmish :
I wanna know who figured this out
2025-12-31 15:45:11
38
cacjunesong
Salamisandwichonrye :
My sister is an organic chemist at RIT on a team studying the “total synthesis of Trocheliophorolide A.” Which is fancy science speak for: making antibiotics out of natural material made by soft coral reefs.
2025-12-31 09:48:29
19
aikr0n
Aeron :
did i hear peptides
2025-12-31 07:13:02
14
red_cg_ward
Clell Gordon Ward Jr :
Begs the question who was the first person to drink milk with a frog sitting in it. 😂
2026-01-02 01:26:32
13
tirztirz_
Tirza Chase :
This explains the frog scene from avatar the last Airbender
2026-01-01 16:50:11
5
castoffzoo
Fur and Feathers 🇨🇦 :
Ok but how does the frog feel about this 😅
2025-12-30 23:26:08
4
prizmoflight
L :
we need to know the whole frog milk process. how long is it left in there?
2025-12-30 21:40:35
34
le.writes
Le.Writes - Author - poetry ✨ :
I’m so glad I live in the 21st century 😂
2025-12-31 04:57:56
21
brightanane_
Bright :
Whose idea was it though 💀?
2025-12-30 19:21:14
23
westernnkid
Richard 🪲 :
I learn so much in this app than school
2025-12-30 21:20:32
5
vkng.wmn
VKNG.WMN :
OK but a silver coin also was used to keep milk from spoiling too back in the day
2025-12-31 11:52:21
14
hpa307
Steven Thompson610 :
does this kill the frog? Don't they drink through their skin?
2025-12-30 19:14:48
34
petambr
animals are people too :
Animals are sentient beings who can feel pain, fear, joy, stress the same way we do, even if they do not speak in human words. It's wrong to exploit them and what they produce for food when there's a huge variety of plant based foods for protein and health
2026-01-01 02:50:59
0
tvobssesion
TV OBSESSION :
Frog slime in skincare? More than 70 peptide beats out every peptide serum currently out there 🙏🏻💕😂
2026-01-01 19:43:20
2
butchboyfriend
butcharchivist :
Did they feed and care for the frogs or just leave them in there?
2026-03-02 16:50:12
1
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