@doctor.asky: Early cartilage changes that begin the first stages of joint degeneration in arthritis. Cartilage begins to break down in an early arthritic joint when the smooth protective surface that covers the ends of bones starts to lose its strength. Healthy cartilage is firm yet flexible. It allows bones to glide without friction. When the joint experiences repeated stress, minor injuries or chemical changes from inflammation, the cells inside the cartilage react. These cells begin releasing enzymes that slowly weaken the collagen and other structural proteins that keep the cartilage firm. As these proteins break apart, the surface becomes softer and less even. The softened cartilage can no longer handle normal pressure. Small cracks appear in the surface. These cracks allow fluid to seep into deeper layers and cause further swelling. The swelling places more stress on the remaining structure. At the same time, the joint lining becomes irritated and produces inflammatory signals. These signals speed up the breakdown of proteins inside the cartilage and make the damage more rapid. As the surface becomes rougher, movement inside the joint creates more friction. This friction irritates the surrounding tissues and increases inflammation. The cycle repeats as weakened cartilage breaks down faster. These early changes mark the beginning of joint degeneration that later becomes more noticeable in arthritis. #science #biology

Doctor ASKY

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Tuesday 17 February 2026 03:35:00 GMT