@dr.rickpescatore: MCAS (Mast Cell Activation Syndrome) and the future of diagnosis and discovery

Dr. Rick Pescatore, BellyMD
Dr. Rick Pescatore, BellyMD
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Region: US
Thursday 19 February 2026 02:23:39 GMT
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hakimjames2
hakimjames2 :
Since covid everyone got gut problems, mcas, leaky gut. ..
2026-02-21 23:50:18
6
brainretraining
Brain Retraining 🇨🇦 :
For me my mcas came into full bloom in perimenopause and seems to be related for me to fluctuating hormones.
2026-02-21 02:34:31
12
imalarper
Lily :
I bet you in 10 years from now there will be enough research to classify MCAS as an AUTOIMMUNE disorder. But maybe I’m wrong 🤷‍♀️🤷‍♀️
2026-07-02 05:49:12
0
natnatnat11111
user2127879140980 :
Digital synthesis of self?
2026-07-02 05:45:13
0
bloodcrusade
bloodcrusade :
I’ve had 4 docs say they think I have MCAS (many symptoms and also have EDS and POTS). Taking H1 and H2 and GPL1s have all helped with symptoms when I’ve taken them. I can’t get an immunologist to either test or if they will they will schedule an appointment for a blood test which show within normal range (I am more symptomatic at night so I probably will never catch it this way). Do you have any advice for those of us trying to get diagnosed?
2026-02-19 05:40:14
8
dr.doodoolicious
Dr. Cher | GI Surgeon :
What do you mean most doctors don’t believe MCAS? Did you mean old doctors or GPs/family doctors? Genuine questions
2026-02-21 16:42:35
10
bellymd_official
Dr. Rick, BellyMD :
Thanks for believing patients and researching these patterns 👏👏👏
2026-02-19 03:18:35
42
ashleywoodsjackson
ash :
I asked our allergist if my my sons food allergies could be related to his collagen disorder (CO2A1) I was told no
2026-02-22 05:17:07
2
shahrukhsy
shahrukh :
What is the evidence for this?
2026-02-19 11:14:36
0
2llamadrama
Kristin :
Thank God I have a wonderful board certified allergist who knows MCAS/Mastocytosis
2026-02-19 03:58:09
12
dreamiewitchy
Laylay🩵 :
mcas makes me allergic to most foods:(
2026-02-20 17:15:46
1
livingwithlupus22
Leslie / LupusLife💪 / TTS 🛍 :
My hemotolgist and immunologist both understand and treat, thank goodness. They did both tell me it's not the easiest to diagnosis and many doctors are not familiar.
2026-02-19 14:51:22
5
taschatrotterturnley
Tascha Trotter Turnl :
I’d like to know your take on Mcas and possible connection to AE, pans,pandas.
2026-02-22 11:01:49
1
aanna.oreilly
A'anna O'Reilly 🌈 :
My mom had lymphedema and hated going to the doctor because so many of them didn't believe that that was a disease.
2026-02-23 10:42:29
3
jacksmarie
Bhavani :
Yes my doctor wanted to medicate me for a panic disorder…that I don’t have 🤦🏻‍♀️
2026-02-28 09:55:21
3
miaobegi
Mia Obegi :
Thank you for not being dismissive. Truly, thank you.
2026-02-19 19:26:03
5
dathepa
KingCona :
medicine is hard.... understanding it at a biochemical level is much more complex and even the best doctors are not perfect. Treating these complex conditions requires being able to identify it and thats sometimes much harder.
2026-02-19 13:47:05
2
user6597107466743
firecracker :
What kind of doctor do you go to get tested for this. I think i have this
2026-02-23 11:41:34
2
sewstratton
sewstratton :
It’s not just histamine
2026-02-21 20:27:39
2
erica_mcafee
Erica Mcafee :
Do you have any recommendations for finding a DR to help diagnose and treat this?
2026-03-05 19:11:44
1
chroniccuteness
Katie Smith :
Thank you for talking about this! I’m lucky to have an allergist/immunologist who listens, cares, and actually treats my illnesses. But outside of that I’m the one teaching my doctors about MCAS so it’s wonderful to see a doctor talking about it!
2026-02-26 07:54:37
2
annbakermodel
AnnBakerModel&Actress :
Those are the doctors I walk away from.
2026-02-23 15:20:59
1
jamiej725
Jamie :
I have HaT genetic mutation and I’m treated for mcas
2026-04-09 21:38:08
1
mamakittiekat
Kat :
My old Allergist MD would only diagnose it off of Tryptase levels. Thank goodness my other Dr's and his RNP in his office felt differently, and went off of my symptoms because in people with MCAS Tryptase is only positive about 50% of the time! 🤦‍♀️Turns out I have MCAS, OAS, and Latex Cross Reactive, the new Allergist who is younger agreed with that diagnosis that my other Dr's and the RNP in the Allergist office had made.
2026-02-21 02:16:55
2
rachelwillow2
rachel ꩜ :
you are an amazing doctor and person thank you so much for validating and believing patients with mcas
2026-02-24 08:04:30
1
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