@1snotdoc: Why does Singulair have a BLACK BOX WARNING? 🚨 The data is more nuanced than the scary headlines. 2025 Swedish study (74k kids): no increased psychiatric risk ✅ Real-world? 16% stopped it in first 2 weeks. Why? Mood. Sleep. Possible self harm. And... it's less effective than first-line drugs anyway. Ask your ENT/allergist: why not steroids + antihistamines first? Don't panic. Just know your options. 📚 Full citations in the comments + our link in bio. #SnotDoc #ENT #Allergy #Singulair #Montelukast
I got prescribed this today with no warning. I have insomnia, anxiety, and depression. Now I'm scared to take it. On steroids & antihistamines already (not working) - this is distressing
2026-07-18 09:09:03
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SnotDoc :
📚 For the nerds who want the data:
[1] FDA DailyMed - Montelukast sodium oral granules/tablets
FDA.gov (mechanism, black box warning label)
[2] Dykewicz et al. 2020 - Diagnosis and management of rhinitis
J Allergy Clin Immunol. 2020;145(4):1049-1072
(First-line: intranasal steroids + antihistamines, not montelukast)
[3] Wintzell et al. 2025 - Montelukast and psychiatric events in children
JAMA Pediatrics. 2025;179(2):e250847
(Swedish cohort n=74,084, no increased psychiatric risk)
[4] Benard et al. 2017 - Real-world asthma/allergy outcomes
Eur Respir J. 2017;50(2):1700509
(16% discontinued montelukast in first 2 weeks: mood, sleep)
[5] Krishnamoorthy et al. 2020 - Montelukast efficacy meta-analysis
Drugs. 2020;80(12):1189-1203
(Less effective than inhaled steroids + antihistamines)
Educational only — always talk to your own doctor 🩺
2026-04-16 20:56:37
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