@adytum_official: Janssen et al. (2016) published in JAMA Psychiatry conducted a randomized, double-blind study on 30 adults with major depressive disorder. A single session of whole-body hyperthermia raising core body temperature to 38.5°C (101.3°F) produced significant antidepressant effects that were apparent within one week and persisted for six weeks. The heat activates the raphe nuclei, stimulating serotonin synthesis through the same system targeted by SSRI medications. Effect sizes were large across all time points. The study included a sham control condition to account for placebo effects. Additional research shows heat exposure also triggers beta-endorphin release and increases brain-derived neurotrophic factor (BDNF) by up to 66%. #MentalHealth #depressionanxiety #SelfCare #sauna #wellness