@drjuhikmdphd: Replying to @ImYoo what labs do we check for lupus or SLE and why? Let’s talk about C3 and C4 the complement proteins that no one talks about enough. These proteins and their levels in your blood can be very helpful in diagnosing lupus or a lupus flare. Send along any questions you have! #lupus #lupuswarrior #autoimmunedisease #medicine
I have Lupus and my C3 & C4 are always normal. No matter if Im flaring.
2026-05-10 01:14:40
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MarshmallowCat :
Positive Ana for lupus, but negative dsdna. What does that mean?
2026-04-22 16:48:15
6
Erica :
what about high c3 and c4 positive ANA with a speckled pattern. plus high sed and esr. mpv high, white blood cells high. every other test normal?
2026-04-22 04:40:17
0
felicia :
can ANA be negative if someone has lupus ??
2026-04-22 23:32:03
5
tidbit10 :
What about high? My total is high and c3 is high. CRP a smidge high.Ana high both homogenous and nucleolar. I can’t find ANY answers online. Seems to be a weird mix of results. No sub component tests for specific diseases are positive. I have hypermobility spectrum disorder too.
2026-05-07 19:15:39
7
Kaylan Tucker :
I am 30 years old and just got a positive ANA with Chromatin. I have symptoms and off and on abnormal bloodwork/issues with kidneys. What is chromatin? I can’t find much on it
2026-05-12 22:25:00
5
harley davis :
what's your take on c3@146, c4@24, positive ana, speckled and homogenous pattern, high ALT, low ACTH.
I'm doing research on lupus and trying to become leveled in the office. all of my symptoms point to lupus but my doctor is hesitant. what's your quick take?
2026-04-22 03:37:34
5
sdpurkey75 :
My wife's C4a is 2850 and her ANA is 1:1280, speckled. Doctors say nothing to worry about, but it seems like it would be. Have you ever seen anything like this?
2026-04-22 20:13:55
6
Health Journeys :
Have you treated for Sjögrens? Wondering if Sjögrens can affect the vocal cords? I got laryngitis out of the blue with no infection(s). I am going on 60 days. I tested + for Sjögrens. But my Rheumatologist said he didn’t know if Sjögrens affects the vocal cords. Thoughts?
2026-04-21 21:38:04
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Lauren :
what if only the c3 is low?
2026-04-21 21:25:07
6
crziebird :
What about when C3 and D-Dimmer are high?
2026-05-07 15:11:53
5
Rach Cutt :
If c3 & c4 are low, but ANA and everything else on lupus panel is normal, what are some of the other differential diagnoses you consider?
2026-04-22 00:22:18
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Kels Morgan :
One of the best explanations I've seen! Thank you 😊
2026-04-22 20:27:46
5
D Marie :
My C3 is normal but my C4 is low…
2026-04-24 15:26:10
5
KarlaEliana :
What other labs do you check?
2026-05-19 12:01:51
5
JDD :
Mine were low and I was diagnosed with sjogrens.
2026-04-24 02:17:00
1
Lilly Acosta :
Can endometriosis cause these test o be slightly elevated ?
2026-04-23 19:08:39
5
danannmsn :
Thank you! So helpful as a primary care NP❤️
2026-04-23 23:01:49
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Megan W :
Great way to break it down. Thank you for this! Easier for my brain to digest 😅
2026-04-21 21:18:32
8
ℒ𝒾𝓃𝒹𝓈ℯ𝓎ℬ⚡️🥀📚 :
🥴 I am wondering if I have it.
2026-08-08 01:34:07
0
crystal_lynn80 :
My C3: 233 (high), my C4: 45 (high) CRP is 24 and my Ana is positive Speckled 1:40
* Spindle apparatus 1:40 WHAT DOES THIS MEAN
2026-05-29 01:40:38
2
ceciliachavira608 :
This was very helpful information. Thank you!
2026-05-09 00:09:49
4
StingerBish :
I’m waiting to see if I have seronegative lupus. All the labs are negative and WNL with the exception of C3 & C4 are both Low. I just want answers for how I’ve been feeling.
2026-06-17 01:50:22
3
DesertRainWorship :
my dr will only check ANA. says if its negative no way I have any autoimmune including lupus.
2026-05-04 01:55:50
3
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