@unwellwilla: Finding the right medication for fibromyalgia is a journey that can take YEARS honestly but for now duloxetine is the one for me. But getting here was NOT easy omg. Have you ever tried it? I really hope this insight helps a bit if you haven’t!!
Pls tell me there’s a magical fibromyalgia medication out there because duloxetine is far from perfect 😅
2026-04-26 22:50:56
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Louise King :
i was on duloxotine 120mg and the side effects were terrible.
2026-04-27 00:41:50
10
leyla08035 :
Hi. I was on amitriptiline last for 3 years. I suffer from a nerve pain. It wasn’t helping that much. I just started 3 days ago doloxetine. I feel the pain is worse. I can’t sleep. I don’t know if I should keep going😒
2026-06-05 06:37:29
0
piaenroth :
I use this for depression. Doesn't help with fibromyalgia at all. Not at all. I use Tramal for fibromyalgia which helps a lot with the pain.
2026-04-27 19:18:48
9
rachel :
I'm on Fentanyl patches since 2007 wich takes the sharp edges of the pain so I can work 2/3 night's a week along with weekly fysiotheraphy and muscle relaxers.I do have a very heavy loaded job in night shifts at age 58 now and 4 more years to go before my retirement. I have been treated for over more than 20 years in several hospitals,painclinics by several specialists and too many kinds of medication wich didn't work.It's a struggle and everyone needs to set his own bounderies.
2026-04-27 15:02:47
5
Harvey Louis :
Did you ever try low dose naltrexone? worked for me
2026-04-28 11:45:55
2
Jess :
I take 25 mg of amitriptyline and 60 mg of duloxetine for nerve pain. We found lowering the dose on both and doing a combo treatment worked better than one alone for me. Not sure if this would work for fibromyalgia too, but could be worth a try? Side effects are still awful months later though, and I fear there’s no avoiding them 😣
2026-04-27 04:25:54
5
Cat_reads🌶️❤️🔥 :
So I suffer mental health as well as fibromyalgia and they put me on duloxetine they are currently in process putting me on max dose but what im struggling with is i feel my mental health has declined badly since being put on duloxetine did find it got better once on right dose if you suffer mental health too? If not its okay xx
2026-04-29 02:38:22
1
💜 Agnes & Her Life 💜 :
I'm on 60mg and it works for me. no side effects st all.
2026-05-30 06:25:07
0
its_hero44 :
I tried the patch “ Butrans” and had allergic reaction. Tried Duloxotine, made me even more tired and soo thirsty. I am on gabapantine, and combination of tramadol/paracetamol when required. It helped me but not preventing flares. I still get flare up that’s when I use the tramadol/paracetamol. I do take separate medication for my migraines.
2026-05-13 16:35:09
2
v :
Everyone reacts different, i take 60mg in the morning and I sleep far better at night. it's not a miracle drug. the first few weeks where worse but now 5 weeks im good.
2026-04-27 08:11:39
5
Sophie Bough530 :
I’m now on 120mg and the horrible mental effects… anxiety and fear of going outside, dark thoughts that I’ve not had for many many years. Just about getting past it now but that’s over 4 weeks of keeping too it! Be strong girl!! 🥰
2026-04-27 21:52:31
3
Zodiac_El :
I have 60mg duloxetine in the morning and 60mg in the evening,I don't think its doing much for me apart from making me wake up every hour through the night 😴
2026-06-04 08:26:53
0
johnyt1972 :
I’m hoping the nhs will approve tomnya (i think i’ve spelt it right).
2026-04-28 07:58:20
3
SJ Allington :
I’m sorry this happened to you. Duloxatine has helped me so much! I have no side effects apart from the odd palpitations but that could also be peri menopause.
2026-04-27 12:47:05
5
Patience :
Had to come off this. Pregabalin gave me my life back however
2026-04-27 12:57:16
6
Linda May :
I haven't found anything that work, my sister thinks I'm a robot as I haven't had any effects from meds at all and definitely no help with pain x
2026-04-27 19:53:44
2
Liv :
How long did it take for you to feel positive impacts from it?
2026-05-29 18:36:45
1
walker_201 :
Nothing works for me
2026-04-29 07:08:07
2
user96028294069242 :
What has it helped with ? Thanks
2026-04-27 21:37:44
2
Kim Seeley :
i was started on this and have been ill for 2 months and cant sleep now
2026-04-27 01:11:42
3
Simon Jones :
im on these I started on 60mg still felt like before I started them now they put me on 120mg about a week ago so let's see if this helps me
2026-04-28 11:58:41
2
JK_Carolinax :
I tried: amytriptyline, lyrica, tramadol, opioid.... Gabapentin, nothing helped at all , since 6 months I'm on duloxetine 60 mg ,2x daily ... first 3 months horrible headache, and stomach pain,nausea...now no headache or stomach issues and I think it took about 30% of pain but everyday is unpredictable.
2026-04-27 22:31:00
3
MonteBanat :
150 mg Trazodone for sleep at night, cyclobenzaprine to manage inflammation, and tramacet (tramadol) for acute flares. I’ve hade fibromyalgia for 34 years. Since I was 22. It’s not perfect, but it has helped me manage.
2026-05-27 08:10:02
1
wendy 🦋 :
I was put on Duloxatine for fibro and had a nervous breakdown on it.
2026-05-24 00:22:04
1
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