@theanthonyvets: Exposure to topical estrogen creams or hormone replacement products can cause significant clinical signs in female dogs, especially puppies. Common effects include vulvar enlargement, swollen mammary glands, hair loss, hyperpigmentation, and signs of estrus. In more severe or prolonged exposures, estrogen toxicity can suppress the bone marrow, leading to anemia, thrombocytopenia, leukopenia, weakness, bleeding tendencies, and life-threatening illness. A thorough household history is important, as accidental exposure often occurs through close contact with owners using topical hormone products. #veterinarian #veterinarianlife #vetmed #vetmedicine #vetmedlife

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