@phluent.app: First new class of hypertension treatments in decades. Great info for all healthcare workers, students, and patients. #Pharmacy #PharmTok #pharmacystudent #pharmacology #hypertension
Appreciate the update. The AHA/ACC guidelines actually recommends long acting thiazide-like diuretics like chlorthalidone and indapamide over HCTZ especially given more recent data showing better efficacy and CV endpoint reductions.
2026-05-29 10:42:38
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kedirabduselam :
Baxdrostat, baxfendy by astrazeneca, is aldostrone synthase inhibitor that calm pressure in blood vessel. what extra advantage does it has than spironolactone if both of them oppose aldostrone?? inhibiting its production is not that much diffrent from blocking its receptor, soecially if there is no such thing called resistance by receptors of aldostrone. so why brand??
2026-05-29 18:00:40
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Robert Nowak :
Just another BigPharma advertisement.
2026-05-30 14:29:33
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Sarah :
Derm PA - curious to see how it acts on acne pts
2026-05-29 22:58:50
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Creative£ :
If only my lecturers while in pharmacy school had such soothing voice.
2026-05-29 06:07:27
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Chilufya🦋. :
just adding on to our study materials😭😭
2026-05-30 14:12:25
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Alhaji Sumaila✅ :
What benefit does it have over spirinolactone?
2026-05-30 22:41:02
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laura :
really? 2 days before my cardio final? they might ask about this, that's how messed up they are😭
2026-05-30 19:57:06
5
Dr. Sihle Mdima (Zuma). :
we need once off cure not drugs
2026-06-03 04:56:29
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M :
She talks a lot 😅
2026-05-30 18:28:58
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Spectre.LV426 🇨🇦 :
this was insightful as someone with high blood pressure since age 28. I'm guessing that first line drugs are still considered very effective and the new drug is really just another options for worse cases?
2026-05-31 03:04:00
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Izzul Izzuddin Shah Abd Rahman :
So since its basically act the same as spironolactone, can it be used as one of the pillars in the 4 pillars of heart failure?
2026-05-29 08:57:12
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Kelvin 🇨🇦 :
Great review of the classes 👍
2026-05-31 20:29:34
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sophie_hall__ :
The guidelines still do not include Aldosterone Synthase inhibitor yet as of 2026.
2026-06-06 14:49:29
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r33d4 :
pharmacist and ex pharma sales rep here, we heard about it back in the early 2020s, the Cardiologists that i used to see were very optimistic, i hope it solves the problem of resistant Hypertension, now that I work in a pharmacy i'm seeing more and more of those unfortunately
2026-05-29 22:09:15
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bs04 :
can't wait for it to be prescribed and be denied by insurance 100% of the time and require a copay that is like $500 a month
2026-05-30 05:17:41
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premsing88 :
is this new one renoprotective? such as Ace-i & arbs?
2026-05-30 03:54:52
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Dr. Tim :
I rarely use spironolactone (for hypertension) unless there’s some concomitant heart failure, combined hypokalemia with another fluid overload state, etc. In fact, I usually go to the alpha blockers before using spironolactone just because of electrolyte issues. I get it that it is a brand new class, but why use this new drug spironolactone? Are there any head-to-head studies between spironolactone and this one? Is the side effect data better?
2026-05-30 19:15:26
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Blue_Robin :
Does it actually cure hypertension??? Why isn't there a cure yet after all this time?
2026-05-29 10:33:18
1
Victoria :
my mother 14 years suffering hypertension 😥..can they be found in kenya?
2026-05-31 14:53:39
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Jah Mere :
Why USA doesn't use Urapidil for hypertension? 😅
2026-05-31 02:45:29
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Only.High.Yield :
Is there any advantage over the receptor blocker?
2026-05-29 22:14:36
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