@mamadosmm: Insulin & Type 1 Diabetes | Discovery of Insulin & DKA Explained القصة التاريخية لاكتشاف الإنسولين التي غيرت الطب إلى الأبد مع د.محمد علاء الدين لا تنسو الاشتراك بقناتنا على يوتيوب Mamado's Medical Media ما هو الإنسولين؟ الإنسولين هرمون يُفرز من خلايا في البنكرياس Beta cells in the islets of Langerhans 📌 وظائفه الأساسية: ✔️ تقليل مستوى السكر في الدم ✔️ إدخال الجلوكوز إلى الخلايا ✔️ تخزين الطاقة In this endocrinology & physiology video 🩺🍬We explain:Insulin & Type 1 Diabetes Mellitus including the historic discovery of insulin in 1921. 🔹 What is Insulin?Insulin is an: ⚡ Anabolic Hormone Produced by pancreatic beta cells. Functions include: ✔️ Lowering blood glucose ✔️ Promoting glucose uptake ✔️ Energy storage📜 Before Insulin Discovery Before 1920, Type 1 diabetes was usually fatal. 🔬 Frederick Allen Used a severe: ⚠️ Starvation Diet Which caused: Severe malnutrition Weight loss Death in many patients 🧪 Discovery of Insulin (1921)By: 👨‍🔬 Frederick Banting 👨‍🔬 Charles Best 🐶 Dog Experiments Pancreas removal caused diabetes Pancreatic extracts lowered glucose 👦 First Human Success Insulin was tested successfully in children with Type 1 diabetes. 🔹 Effects of Insulin🍞 Carbohydrates Increases glucose uptake Increases glycogenesis💪 Proteins Promotes protein synthesis🧈 Lipids Promotes fat storage Decreases ketone production 💉 Types of Insulin Rapid acting Short acting Intermediate acting Long acting 🔴 Type 1 Diabetes Mellitus Autoimmune destruction of beta cells causing severe insulin deficiency. ⚠️ Symptoms : Polyuria Polydipsia Polyphagia Weight loss ⚠️ Diabetic Ketoacidosis (DKA) : A dangerous complication caused by insulin deficiency. Symptoms include: Vomiting Dehydration Fruity breath odor Kussmaul respiration 🎯 Essential for endocrinology, physiology, and clinical medicine. -------------------- #صحة #طلاب_طب #medicine #Insulin #fyp

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