Dr. Michael Richman MD
Region: US
Sunday 31 May 2026 01:25:33 GMT
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theforgottenonestravel :
I'd like to hear more about mcas. I was diagnosed 6yrs ago after a t0xic m0ld exposure. let's explore environmental!
2026-06-21 08:47:28
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Morgan Gray :
I was able to get a clinical diagnosis because my symptoms were so severe and I improved with cromolyn sodium and antihistamines. I was incredibly, incredibly sick for about a year, and couldn’t even get in to have my labs checked. I was locked in one room of my house for an entire month. Stable now, though.
2026-06-23 02:03:13
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Jennifer Barrett :
Can you touch on the connection between EDS and MCAS? Since mast cells are released into connective tissue and people with EDS have compromised connective tissue wouldn’t that be a cause? Or just a predisposition? 2/3 of people with EDS have some degree of MCAS so I don’t see how we haven’t made the connection?
2026-06-25 12:33:09
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K :
Please research central dysautonomia -> neurogenic MCAS cascade. It’s very real.
2026-06-22 11:33:52
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Rissa :
levoquin did it to me
2026-06-05 11:45:12
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Christy. :
once I had a 3 hr delayed anaphylaxis.
2026-06-01 21:28:01
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D :
What board certification specializes in MCAS?
2026-05-31 02:39:20
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Lisie♥️cici :
Wondering the differences between qualifying for MCAS vs someone who struggles with an overload of histamine. Dermagraphism, frequent rosacea flares, scratchy throat, itchy skin, headaches, tight lungs, responds well to antihistamines and albuterol but no anaphylaxis.
2026-06-01 16:02:32
1
bluesky :
Yeah. I have urticaria vasculitis and every symptom known with MCAS. I carry an epi pen and I can’t get diagnosed because my tryptase is low. I also wasn’t flaring when the blood work was taken. And not ALL low tryptase means no MCAS.
2026-06-20 15:32:54
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Jamie Williams - REMAX :
Covid got me in 21.
2026-06-19 12:23:18
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HHH1935 :
For years I was being screened for Carcinoid syndrome-even the octreotide test didn’t rule it out but MCAS was that diagnosis along with Sjogren’s Disease🤔
2026-06-01 18:19:52
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Kare :
yep, thats what im dealing with. Im all ears.
2026-06-02 00:45:26
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spfprotective :
Ty
2026-06-17 02:17:40
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Chelsey Sterling :
Thank you for talking about this!! I was diagnosed with this by my immunologist and I don’t really understand it. And most of the information online is bad. 😂
2026-05-31 06:48:29
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natmcb :
Thank you for explaining this thoroughly!
2026-06-01 15:08:02
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Lee :
I have learned so much thank you dear !
2026-05-31 14:49:01
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Henry Obst :
The most common problem with MCAS is 99.9999% of doctors will tell you it’s just anxiety. There’s absolutely no point in going to the doctor to have them gaslight you about this. Best to do your own research and figure out how to fix it yourself
2026-06-05 14:38:25
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nikkicnavigatinglife :
ITs 100% Real - and it’s hell and a bad joke
2026-06-19 11:13:11
1
b3au :
Thank you for speaking on this! In doing so it’s also prudent to discuss the relationships between MCAS, hereditary alpha tryptasemia (HaT), and Systemic Mastocytosis. They are not mutually exclusive, there is symptom overlap and treatment overlap as well, aside from the TKI protocols for SM. I personally would like to see more research into why there seems to be a correlation between EDS and various mast cell disorders. I won the lottery with confirmed diagnoses of SM (KIT Postive & bone marrow biopsy), HaT (genetic testing), and MCAS. I had so many providers dismiss my symptoms as well as my experience for nearly a decade. Thank God for research hospitals. If you struggle with symptoms or suspect these conditions don’t give up. tmsforacure.org is a phenomenal resource. There are new therapies being approved all the time. I participate in a clinical trial of a TKI for systemic mastocytosis and the drug has been approved for release this December. In addition my daily regimen includes cetirizine, famotidine, montelukast, cromolyn, azelastine nasal spray, oral ketotifen (can be prescribed IN THE US but must be compounded as it’s not fda approved for oral use yet), budesonide (nasal spray), symbicort inhaler, omeprazole, weekly omalizumab (xolair) injections, and prednisone for flares. Each of these are meds are in my opinion an imperative part of a successful mast cell disease regimen. There are natural supplements like quercetin that can be beneficial also but you have to check interactions.
2026-06-15 09:44:04
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inneruhealthwellness :
We do know that certain overgrowths of dysbiotic flora like pseudomonas and klebsiella can increase the amount of circulating histamine. I believe the answer is going to be in the microbiome.
2026-05-31 15:35:05
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lindathrasher1 :
What can a person do, if someone is having a mast cell activation? Provide Benadryl?
2026-05-31 22:52:34
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Beautiful wom¢ns :
🥰🥰🥰
2026-05-31 11:29:45
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fylgjafox :
❤️❤️❤️
2026-05-31 18:04:04
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