1. Home
  2. Detail

@psfive45: The best sound cars #perfect #sound #look #forzahorizon5go #gameplay

PS5
PS5
Open In TikTok:
Region: GB
Tuesday 09 June 2026 07:00:11 GMT
33038
237
3
5

Music

Download

No Watermark .mp4 (10.35MB) No Watermark(HD) .mp4 (9.71MB) Watermark .mp4 (10.54MB) Music .mp3

Comments

bipugrg6
BIPU :
😂😂😂
2026-06-11 08:53:38
0
willmudug2
Maryamo :
🤩🤩🤩
2026-06-09 18:20:56
0
xaliimo.xasan176
xaliimo xasan :
😳😳😳
2026-06-11 16:52:41
0
To see more videos from user @psfive45, please go to the Tikwm homepage.

Other Videos

ORTUSEIGHT JOGOSALA RAMPAGE V4 betul ke sampah?#futsalchuteiras #ortuseight
ORTUSEIGHT JOGOSALA RAMPAGE V4 betul ke sampah?#futsalchuteiras #ortuseight
hEDS has traditionally been classified as a connective tissue disorder defined by joint hypermobility. This framing never fully explained why hEDS so often comes with immune dysfunction, dysautonomia, and chronic fatigue. New genetic research is reframing it as a multi-system condition. A 2025 study by Gensemer et al. in iScience (MUSC, Norris lab) performed whole-exome sequencing on 200 hEDS patients and identified a recurrent variant in KLK15, a gene active in both connective tissue and immune tissue. A knock-in mouse with the variant developed connective tissue abnormalities in tendons and heart valves alongside dysregulated cytokine signaling. A separate 2026 study by Shirvani et al. in Genes found hEDS-associated variants enriched across three systems: collagen biosynthesis, HLA/immune pathways, and mitochondrial function. KLK15 is described as a contributor, not a confirmed single cause. The variant was found in roughly a third of patients, and hEDS remains genetically complex. This research does not yet enable a genetic test for hEDS, and the 2017 clinical criteria remain the standard for diagnosis. The multi-system genetic paper used machine learning on a single cohort and needs replication. I’m not a doctor, just sharing research I find interesting. Sources: Gensemer et al. (2025). iScience. DOI: 10.1016/j.isci.2025.113343 Shirvani et al. (2026). Genes. DOI: 10.3390/genes17020211 #heds #ehlersdanlos #chronicillness #hypermobileehlersdanlossyndrome
hEDS has traditionally been classified as a connective tissue disorder defined by joint hypermobility. This framing never fully explained why hEDS so often comes with immune dysfunction, dysautonomia, and chronic fatigue. New genetic research is reframing it as a multi-system condition. A 2025 study by Gensemer et al. in iScience (MUSC, Norris lab) performed whole-exome sequencing on 200 hEDS patients and identified a recurrent variant in KLK15, a gene active in both connective tissue and immune tissue. A knock-in mouse with the variant developed connective tissue abnormalities in tendons and heart valves alongside dysregulated cytokine signaling. A separate 2026 study by Shirvani et al. in Genes found hEDS-associated variants enriched across three systems: collagen biosynthesis, HLA/immune pathways, and mitochondrial function. KLK15 is described as a contributor, not a confirmed single cause. The variant was found in roughly a third of patients, and hEDS remains genetically complex. This research does not yet enable a genetic test for hEDS, and the 2017 clinical criteria remain the standard for diagnosis. The multi-system genetic paper used machine learning on a single cohort and needs replication. I’m not a doctor, just sharing research I find interesting. Sources: Gensemer et al. (2025). iScience. DOI: 10.1016/j.isci.2025.113343 Shirvani et al. (2026). Genes. DOI: 10.3390/genes17020211 #heds #ehlersdanlos #chronicillness #hypermobileehlersdanlossyndrome
#شعب_الصيني_ماله_حل😂😂
#شعب_الصيني_ماله_حل😂😂
#fyp #fypシ #foryoupage #viral #creatorsearchinsights best English movie scene
#fyp #fypシ #foryoupage #viral #creatorsearchinsights best English movie scene
boa reputação com os clientes #negocios #mrv #rubensmenincy
boa reputação com os clientes #negocios #mrv #rubensmenincy
She a little unstable but I had to switch editting programs 😞 #soldiebutch #butcherboy #theboys #theboysedit #soldierboy #jensenackles #billybutcher #karlurban
She a little unstable but I had to switch editting programs 😞 #soldiebutch #butcherboy #theboys #theboysedit #soldierboy #jensenackles #billybutcher #karlurban

About

Legal