@mtn.alice: To LEEP or not to LEEP, that is the question 😵‍💫 Doctors diagnose these cellular changes by doing your yearly pap smear and then a colposcopy to formally diagnose it! This is why it's essential to never skip a pap. I am a perfectly healthy young person who doesn't smoke, drink, exercises a ton, eats pretty good, don't have any genetic predispositions (got genetic testing last year), etc etc etc and this is STILL something I'm dealing with! Don't assume you're healthy, take advantage of preventative screening. How lucky are we to live in the modern world where these tiny changes can be detected before it's even remotely close to being cancer. It's pretty cool if ya think about it! Fun facts that I learned while researching *sources in comments*: -CIN2 still has about a 60% chance of spontaneously regressing on its own! These odds go down for high risk HPV strains and the odds go up (to ~85%) if you are younger than 30--ideally younger than 25--and if you got the HPV vaccine before 15 years old -For people with CIN1, there are promising studies about supplementing with EGCG, folic acid, b12, and hyaluronic acid over 6 months to clear up these changes. These supplements are quite cheap and the studies, though limited, seem promising (and don't have conflicts of interest/not funded by the supp companies) -Since 2013, Denmark has changed their guidelines and allows women to opt for a LEEP right away OR do active surveillance for 15-24 months. 2-year treatment outcomes show that the risk for cervical cancer is similar across these two groups, however, over the long term (like over the span of 20 years) people who do not do the LEEP are higher risk. -Doing the LEEP increases the risk of preterm labor/miscarriage. This is more relevant for people who intend to get pregnant in the 12 months post-LEEP. I can't say those are my plans for the year, or really like the next five, but it's still something I care about. As always, my comment section is not a place for your medical war stories so let's keep it positive and encouraging thanks!!! Papers to check out 🦠🧬🧪 1. Krog L, Lycke KD, Kahlert J, et al. Risk of progression of cervical intraepithelial neoplasia grade 2 human papillomavirus--vaccinated and unvaccinated women: a population-based cohort study. Am J Obstet Gynecol 2024;230:430.e1-11 2. Kyleback K, Ekeryd-Andalen A, Greppe C, et al. Active expectancy for cervical intraepithelial neoplasia grade 2 in women aged 25 to 30 years. Am J Obstet Gynecol 2022;227:742.e1-11 3. Porcaro, G., et al. Oral treatment with egg, folic acid, vitamin b12, and hyaluronic acid improves HPV clearance and counteracts its persistence. Int J Mol Sci 2025, 26, 5251 4. Lycke KD et al. Untreated cervical intraepithelial neoplasia grade 2 and subsequent risk of cervical cancer: population-based cohort study. BMJ 2023;383:e075925

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Thursday 11 June 2026 16:15:45 GMT