@chemmunity: How would you solve this synthesis problem? There are multiple different ways you can approach this, so let us know in the comments! #organicchemistry #premed #study #ochem #chemistry
the chemistry steps are solid but i wish our state budget had this much lotic @herb4controller
2026-09-08 22:45:46
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Andrew ⚓️ :
1) PCC/CH2Cl2
2) CH3CH2MgBr
Right?
2026-06-30 15:41:30
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BeatsbyDad :
Guys you can’t add EtMgBr to the aldehyde (upon oxidation of alcohol). The grignard will over add to the aldehyde to afford a tertiary alcohol. The way in the video is the most simplistic way
2026-08-13 17:37:01
1
Iñaki ciencia 🧪🧪🔬🔬⚛️⚛️ :
First oxidation of the alcohol to an aldehyde with PCC/CH2Cl2. Once oxidated the alcohol to aldehyde, It Will pass through a 1,2-addition with Grignard reactant, producing a secondary alcohol and finally PCC/CH2Cl Will give a ketone
2026-08-27 13:22:06
1
ArieCurtis :
wait is the grignard addition to the aldehyde a problem here? i thought that was the whole point
2026-09-01 21:29:57
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fvckcops :
I’m bad at this stuff 😅
2026-09-06 16:23:11
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Jesper Allaer :
Oxidation to the aldehyde with Swern or DMP, followed by Grignard and another oxidation with Swern or DMP is probably less toxic than using Chromium reagents
2026-06-30 16:04:57
2
Sara♡︎ :
What about 1. PCC, 2. EtBrMg, 3. PCC
2026-08-07 14:35:09
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gg_equals_gitgud :
PBr3 then Mg, aldehyde, pcc
2026-06-30 17:49:31
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1920 :
or we could do it this way 😅
2026-06-30 15:38:30
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blaxkghost0 :
Where do yall get these intermediates from
2026-07-14 19:26:47
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Iroh :
everyone likes Grignard reagents
2026-06-30 16:47:37
3
Itsmelydiyah💋! :
@Adeline
2026-09-05 22:34:52
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