Acetaminophen for fever
Ibuprofen for inflammation
2026-07-14 00:58:20
1056
Ben McDaniel :
So if something worked for 30% of people in a study, does that imply it works 30% of the time for everyone, or does that mean it works all the time for 30% of people (or somewhere in between, like works 50% of the time for 60% of people)? Depending on the answer, the drug that studies show is less effective might always be the right choice for certain patients (if you already know it works for them).
2026-07-25 14:47:15
0
Morticia.Frizzle🆓🇺🇸🆘 :
Omg I’ve always sworn Tylenol does absolutely nothing for my pain and people argue with me that it’s just as effective as ibuprofen and it’s just in my head. I feel SO validated right now.
2026-07-14 05:20:51
746
Dani's at home :
sometimes ibuprofen and aspirin work better togetherfor me for headaches
2026-07-25 09:11:09
0
Zoobies88 :
They need to stop putting Tylenol in things. They should just suggest you take it separately.
2026-07-25 15:03:00
1
JerryJones2000 :
wish you talked about Naproxen in this same context.
2026-07-14 16:30:46
109
Garden Tarot :
what about powdered aspirin packets like BC packets? Post foot surgery they were far more effective than 800mg of ibuprofen for me. Just curious if you've read? Love ur page! (if youre too busy to see this, I am so okay with that) 😊
2026-07-24 03:01:25
1
JJ56789 :
MD Pain physician here. look at the Oxford analgesia league tables. In blinded studies Opioids aren’t that great. Ibuprofen beats moderate morphine doses for dental pain. Ditto acetaminophen vs lower opiod doses. Opioids are really not that effective in blinded studies (massive placebo benefit) - but their benefit as an agonist you can just increase the dose as needed until either pain free or unconscious . NSAIDs block an enzyme meaning there’s a ceiling- once that enzyme fully blocked can’t block it anymore
2026-07-14 10:59:02
215
Abby Dabbs :
I have always preferred ibuprofen
2026-07-14 07:13:38
125
forbiddengypsy :
did you say sodium channels? what do you know about the brain workings like deep stuff 😁🥰🥰
im all for brain facts lol. thank you for the continued lessons
can you refer me to a super in depth neuro for fun facts lol
2026-07-24 22:34:42
0
TanglesTheRope :
Fun fact that she knows that you won’t know, cocaine is not illegal in every format. There’s actually a topical spray version of cocaine that we use in the operating room, and it’s a vasal constructor, meaning that it shrinks your blood vessel so you don’t bleed very much. We use it very, very often in surgeries in and around your mouth and throat because of how much bleeding happens in those areas. The good news is, that formulation of the drug is not something you could get high off of even if you misuse it. And, by the time it’s being sprayed on your throat, you’re definitely already anesthetized.
2026-07-14 09:03:08
30
failenaa :
the menstrual pain one is hilarious bc the medication specifically marketed for it is literally acetaminophen and caffeine. 😂 but i’ve always found ibuprofen works better. i think ibuprofen is good for cramping/strain related pain as well.
2026-07-14 10:26:17
80
lia :
I have never felt much of any effect from acetaminophen for headache or period cramps or anything whereas ibuprofen helps significantly, this is so validating. Why is it still legal and commonly used though if it doesn’t have much efficacy and causes a lot of harm across the population?
2026-07-24 05:50:23
3
Zappa🇨🇦 :
Acetaminophen also has a very close Therapeutic Dose/Toxic Dose gap, so even the "recommended safe dose" could potentially cause a lot of liver damage based on how the body metabolizes it - even without prior history of liver issues.
2026-07-15 06:47:19
14
Kit Vixen 🦊 :
honestly I wish I could show this whole video to every medical profession I've ever seen. "have you tried Advil/Tylenol?" of course I've tried the very common OTC medicine! I wouldn't be here if it worked! and now I know I was right!
2026-07-14 05:45:45
80
J. Hrebinka (Shanahan) :
Living in Europe where I got screamed at by a doc for taking 800mg of ibuprofen and then told to take 1000mg of Tylenol every 6h 😑 bad doc aside, they're so delicate about ibuprofen here but tylenol is just the de facto treatment for everything
2026-07-15 06:24:06
11
Leah Behr :
what about naproxen? that works better across the board better than either tylenol and ibuprofen for me.
2026-07-14 22:46:33
4
lupe :
you should talk about metamizole/dypirone! it boggles my mind the amount of contries where it isn't avaliable considering how its been show to be safer and its effective
2026-07-14 01:49:36
1
e :
ive always took both of them together for general pain cramps and headaches I think it might be a cultural difference from nz to the usa
2026-07-15 13:40:41
5
Gemstone rings :
Naproxen is my life safer for migraine
2026-07-15 10:29:14
7
Alphabet Suwup :
This is so interesting as an EMS worker! Anecdotally, our patients seem to get a much greater level of relief from IV acetaminophen compared to IV fentanyl or morphine or ketamine. However the greatest amount of pain relief was found to come from a combo of acetaminophen and ketamine. Of course, these patients had something more significant going on than just a typical headache or ankle pain, but still super intriguing how route of admin and possibly environment play a factor.
2026-07-14 18:05:50
8
Samjay7795 :
For me I’ve found acetaminophen works for my headaches and migraines (plus triptans) but ibuprofen for muscles and cramps
2026-07-14 11:29:12
20
Melissa :
Naproxen is where it’s at if I need pain relief. The others are just if I’d like the edge off. 🫠
2026-07-14 07:56:38
6
Introvertebrate32 :
I would love it if you talked about why acetaminophen is paired with oxycodone for pain medication (percocet), and why that is prescribed for chronic pain over just a oxycodone of the same dose?
2026-07-15 01:09:46
5
EFTHYPNOTHERAPY :
You need to do a video comparing aspirin, naproxen and Toradol. Yes, I know Toradol is by prescription. The point is to talk more about other NSAIDS.
2026-07-14 20:19:22
9
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