@cbseveningnews: The FDA has approved a new daily cholesterol pill that works differently than statins and could offer another treatment option for some patients. Tony Dokoupil spoke with a Columbia University cardiologist. #cholesterol #FDA #health #healthtok

user7650724595019 :

She didn’t explain the the pharmacology of the 2nd drug. They should’ve just interviewed a pharmacist

Griff :

Pharmacist here! Lipfendra binds to the same receptors as those injections, which are monoclonal antibodies. This is a macrocyclic peptide, a big chain of amino acids that loop together. PCSK9 binds to LDL (bad cholesterol) receptors, which prevents it from being cleared from your blood. By inhibiting PCSK9, we can give more openings for LDL to bind and clear from the blood. And now, it’s oral! Pretty cool (but expensive).

ohpariss✨ :

This comment section makes me SO happy i'm a pharmacist🥰😍😍

Poona ❤️ :

Insurance please cover this 😭

kristinrals :

PCSK9 inhibitors have been out for years! It’s just a breakthrough because this formulation can be taken as a pill :)

Ash :

lol at everyone nervous about this mechanism of action like Repatha and Praluent haven’t been out for 10+ years. It’s just the oral version of an established injection. Same as the GLP1s transitioning to oral administration..

haylee :

Already not accurate source, have a PharmD not a MD explain this, doctors of PHARMACY. Shows this news station uses false information and lies to boost an agenda. Lies!!!!!

ZaksTravels :

Is this a pill version of Repatha?

Lauren Flood :

The pharmacist love in these comments makes me so happy 🥹

Nicole 🇨🇦 :

How about just eating a plant based diet instead.

KrisFom :

I’m so sick of waiting !!!! I am pretty healthy. Even weight not overweight. I have HIGH cholesterol and EXTREMELY HIGH LPa gene, 465!!! I am a ticking time bomb because no one seems to concerned!! I’m concerned!!!!

Tonya Jean :

FYI - if you want to take this new medication and you want your insurance to pay for it, I can assure you that the vast majority of medication plans will not cover it unless you have tried and failed other cheaper, older meds for cholesterol. And if you have to pay cash out-of-pocket, it’s going to cost you hundreds if not thousands of dollars

seantremusic :

What are the side effects? Does it cause other things?

OldVoice :

🤷🏻‍♂️and yet we still don't know how it differs from statins after this report.

zeldrs :

This is good but raw milk is bad 🤔

jaaantoniooo :

Repatha injection and now it’s PO Lipfendra

𝓣𝓸𝓻𝓲 ♠️🃏 :

yeah idk i wouldn’t trust anything new anytime soon

dr.erindo :

We already have PCSK-9 inhibitors. This will cost patients hundreds of dollars a month, and make them questions statins all together. What’s truly the difference between this and a statin? It will only reduce adherence to medication.

Joe M :

And what makes this drug in pill form better than the pills that are still in the market? It’s a different mechanism to lower cholesterol, but what is the benefit of any?

crown_queen_nothing01 :

greathdeath2all :

now remove chemical from food

C.Vanderbilt :

Another “Daily use” to add to the cost!? It’s as if Farma created what works to get us to now pay per day instead of monthly… 😏🙄🤬

Linda :

What are the side affects?

Thomas Cheeseman :

👍

G :

This seems like a bad idea