@jojoyourboat: Please…. Stop… save your money#wellness #fyp #weightloss #trend 1. Yakub K, Palikhe S, Iqbal T, et al. Nicotinamide Riboside and Nicotinamide Mononucleotide Facilitate NAD+ Synthesis via Enterohepatic Circulation. Science Advances. 2025. 2. Wakabayashi J, Higashi S, Morifuji M. Sublingual NMN Administration Increases Early Circulating Terminal Metabolites Compared With Oral Administration in Healthy Adult Men. Scientific Reports. 2026. 3. Zhang D, Yau LF, Bai LB, et al. Hydroxyapatite-Based Nano-Drug Delivery System for Nicotinamide Mononucleotide (NMN): Significantly Enhancing NMN Bioavailability and Replenishing In Vivo Nicotinamide Adenine Dinucleotide (NAD+) Levels. International Journal of Pharmaceutics. 2023. 4. Xiao K, Nakagawa T. NAD+ Precursors in Human Health and Disease: Current Status and Future Prospects. Redox Biology. 2023. 5. Kim LJ, Chalmers TJ, Madawala R, et al. Host-Microbiome Interactions in Nicotinamide Mononucleotide (NMN) Deamidation. FEBS Letters. 2023. 6. Ratajczak J, Trammell SAJ, et al. NRK1 Controls Nicotinamide Mononucleotide and Nicotinamide Riboside Metabolism in Mammalian Cells. Nature Communications. 2016. 7. Fletcher RS, Ratajczak J, Doig CL, et al. Nicotinamide Riboside Kinases Display Redundancy in Mediating Nicotinamide Mononucleotide and Nicotinamide Riboside Metabolism in Skeletal Muscle Cells. Molecular Metabolism. 2017. 8. Fan R, Cui J, Ren F, et al. Overexpression of NRK1 Ameliorates Diet- and Age-Induced Hepatic Steatosis and Insulin Resistance. Biochemical and Biophysical Research Communications. 2018. 9. Bounvicino D, Ranieri G, Pittelli M, et al. SIRT1-Dependent Restoration of NAD+ Homeostasis After Increased Extracellular NAD+ Exposure. Journal of Biological Chemistry. 2021. 10. Yoshino J, Baur JA, Imai SI. NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR. Cell Metabolism. 2018. 11. Kropotova A, Kulikova V, Solovyeva L, et al. Purine Nucleoside Phosphorylase Controls Nicotinamide Riboside Metabolism in Mammalian Cells. Journal of Biological Chemistry. 2022. 12. Sun JY, Wang ZF, Xu WH, Zhao J. NAD+ Glycohydrolase/CD38 as a Therapeutic Target in Aging: Physiological Roles, Molecular Mechanisms, and Future Opportunities in Anti-Aging Research. Journal of Biochemical Pharmacology. 2025. 13. Tarragó MG, Chini CCS, Kanamori KS, et al. A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD+ Decline. Cell Metabolism. 2018. 14. Grozio A, Sociali G, Sturla L, et al. CD73 Protein as a Source of Extracellular Precursors for Sustained NAD+ Biosynthesis in FK866-Treated Tumor Cells. Journal of Biological Chemistry. 2013. 15. Escande C, Nin V, Price NL, et al. Flavonoid Apigenin Is an Inhibitor of the NAD+ase CD38: Implications for Cellular NAD+ Metabolism, Protein Acetylation, and Treatment of Metabolic Syndrome. Diabetes. 2013. 16. Deng C, Liu J, Hou M, Deng Y, et al. Double-Prolonged NAD Preservation: Delaying Cellular Senescence and Initiating Musculoskeletal Regeneration. Aging Cell. 2026. 17. Zhang Z, Ansari AJ, Fayne ER, et al. Emerging Medicinal Strategies for CD38 Inhibition: Restoring NAD+ Metabolism and Disease Control. Bioorganic & Medicinal Chemistry. 2026. 18. Sun X, Su L, Bu T, Zhang Y. Exercise Training Upregulates Intracellular Nicotinamide Phosphoribosyltransferase Expression in Humans: A Systematic Review With Meta-Analysis. Frontiers in Public Health. 2023. 19. Costford SR, Bajpeyi S, Pasarica M, et al. Skeletal Muscle NAMPT Is Induced by Exercise in Humans. American Journal of Physiology. 2010. 20. Gallagher C, Emmanuel OO. NAD+ Supplementation for Anti-Aging and Wellness: A PRISMA-Guided Systematic Review of Preclinical and Clinical Evidence. Ageing Research Reviews. 2026. 21. Wei D, Huang Y, Shi D, et al. Structure Guided Engineering of Bifunction Enzyme NadR for Enhanced Nicotinamide Adenine Dinucleotide Production. Biotechnology and Bioengineering. 2026. 22. Manickam R, Tur J, Badole SL, et al. NAMPT Activator P7C3

drjojoyourboat
drjojoyourboat
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Tuesday 28 July 2026 18:03:56 GMT
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jenna_ruth_
Jenna Ruth Clough :
Do you suggest a NMN supplement?
2026-08-16 12:52:33
1
ecaf33
ecaf :
Honestly amazing, can you go in depth and debunking other peptides like, tb500, bpc, gluthathione, ghkcu, etc.
2026-07-28 18:24:10
17
idfcaaysb
Kbunni :
Thank youuuu 🙏🏻🙏🏻
2026-09-29 16:40:13
0
whitakajoaquin
Whit Guerrero :
Well it actually helps a lot of people a lot to feel better so that’s why people are taking it
2026-08-30 02:07:15
6
wannabsahm
WANNAB SAHM | UGC :
My question is does raising NAD levels even if done via NMN, also increase the risk of any possible cancerous/ tumor growth you unknowingly already have? So many doctors giving conflicting responses on this.
2026-08-22 22:00:46
5
nijemabdel
Abdel :
Thoughts on glutathione?
2026-07-28 18:13:09
2
lifttillimdead
Lifttillimdead :
I’m getting my popcorn😈
2026-07-28 18:17:08
4
watdemfeetdo
Watdemfeetdo :
I use the NAD nasal spray. I feel like it has helped me in training for my iron man🙂‍↕️
2026-07-28 22:58:12
2
thebrandonchou
Brandonch0u :
Would the cellular uptake increase if you take Apigenin a CD38 inhibitor? Very curious thanks!
2026-08-13 05:01:07
1
dagaman01
Vic :
If taken orally
2026-09-03 15:04:23
0
nuhnsz
nuhnsz :
Opinion on Tru Niagen??
2026-07-30 04:00:47
0
kristilanette5
kristilanette :
How do you feel about SS31?
2026-08-16 16:33:18
1
britt.darling
britt.darling :
Had an issue last year where multiple pharmacies were reporting high levels of endotoxins in the NAD product powder. So dumb all around.
2026-08-13 20:45:00
1
velliemauge
velliemauge :
the eyes are so beautiful 🥰
2026-07-30 02:40:56
1
nyc_ai.ch
.NYC.AI.CH.🇺🇸 :
lol
2026-07-30 00:49:57
1
amierhaidarmd
Amier Haidar | Cards Fellow 🫀 :
Thank you for this 🙏
2026-07-29 02:27:23
1
jayysoroo
jayden :
Oh
2026-09-17 21:35:08
0
angsf691
AngelaSF🤓 :
Thank you!!!
2026-09-19 00:40:12
0
toyatheeexplorer
Toya the Explorer :
Is this the same for NAD+ AND NADH?
2026-09-15 18:03:08
0
maybesomewherethere
K :
I disagree. I have an autoimmune condition and NAD plus has been a game changer for me. It also indirectly helped me with my gastric emptying. It’s not a scam but your bias is a scam
2026-08-19 04:53:20
2
user3694581817222
perrygrip :
your cars not moving why keep looking ahead
2026-09-14 08:32:29
1
sarcastichousewife
Elise Leet :
I think it gained a ton of traction around Covid. I remember a ton of videos about people that had brain fog saying that NAD infusions cured them.
2026-07-28 18:37:13
3
hiiamkobe
Kobe :
Does Mot c work ?
2026-08-14 04:11:20
1
nurse_25
Mia :
Are you wearing a karate robe? Because you are talking like you’re going into battle. 🥷
2026-08-13 03:01:46
1
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