@datiskharrazian: Hashimoto's Aggressiveness — One Simple Question Most hypothyroidism is autoimmune. The standard protocol assumes ongoing thyroid destruction, so patients return yearly to adjust dosage. But not all Hashimoto's progresses the same way. Ask: How often have you increased your thyroid medication? Annual increases signal active tissue destruction — an aggressive autoimmune response. No increases over five years, despite stable levels, suggests the autoimmunity has quieted. That single question tells you the trajectory of their disease and what intervention approach makes sense. Start your 7-day free trial at clinicalfunctionalmedicine.com