@biomaxxer: SSRIs, neurogenesis, NSI-189 and the wrong target for depression? Now, I’m not saying NSI is proof for ADN and SSRIs are not, but at the very least, this is a potentially much less destructive compound and a promising development for depression and cognitive enhancement (they go hand in hand as I’ve shown.) No beef with SSRI users! Also shout out @Julian as his takes on SSRIs are antithetical to mine and I think you guys should see both sides. #pharmacology #biohacking #neuroscience #nootropics #ssri

Biomaxxer
Biomaxxer
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Saturday 08 August 2026 04:08:57 GMT
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xboorgx
Borg🇸🇪 :
I love fluvoxamine
2026-08-08 07:17:56
7
qhazm
Hayden :
i’ve been on ssris snris and mood stabilizers since 16 to treat bpd and major depressive disorder caused by extremely low testosterone and let me tell you my brain has never been close to as sharp as before i got on ssris when i first started ssris it felt like i had just a chunck of my brain turned off
2026-08-08 05:28:01
28
juublian.neuro
juublian.neuro :
Haha this is a good video, I like discussing both sides here (unless it’s bioscience). I’ll make a stitch soon, but I do think you have a point about more “direct” drugs being more favorable. I wouldn’t be surprised if SSRIs got outclassed by more targeted selective drugs in 30-50 years. The only issue here is the lack of data with these more targeted drugs; they don’t have the 40 years of post-clinical data like SSRIs do. Mechanistic data only goes so far, but it’s important to see all facets here.
2026-08-08 04:40:25
24
harryddddd
Harryd :
What about serataline
2026-08-08 13:41:47
9
vadtaf
vadtaf :
Is Wellbutrin harmful
2026-08-08 05:22:18
1
tantrum999
ger :
Idk I don’t like how much hate antidepressant get cz not everyone even gets those side effects. I’ve tried many antidepressants and I like them quit max dose duloxetine over a year ago and it was fine lowkey needed help again started venlafaxine 2 weeks ago. they just not bad imo way better than depending on benzos and truly help people they not just destructive
2026-08-08 12:26:59
3
rahimrahim6105
rahimrahim6105 :
peat said no
2026-08-09 14:16:22
4
sixthp
Sixth :
Every time I sweat or get hot it feels like I’m being skinned because of taking SSRIs for so long, I don’t even take them anymore too 💔
2026-08-08 23:50:51
3
jzqvns
jzqvns :
i thought ssris cause brain shrinkage/is extremely bad for your brain or am i mistaking it for benzo’s/anxiety meds/antipsychotics
2026-08-20 06:12:40
3
nelson1236688
nelson1236638 :
My friends been on ssris for half his life would that have made him smarter
2026-08-09 08:58:40
1
meinfascesleben
Nach :
Isn’t that leo video like 4 years old as well
2026-08-08 22:31:01
3
itsthejacket
Bekind :
We need a new podcast bro
2026-08-08 13:05:58
1
user3911124779233
perimeter :
wasn't he using it for sigma 1 agonism more so?
2026-08-19 18:41:42
1
andyyymor
Andymor :
I got on fluvox and everything felt better . Look up the dominance hierarchy and serotonin and I found a bunch of studies that show wayy more increase in neurogenesis . Normally I like his videos but this isn’t the best take.
2026-08-11 17:02:19
4
good.goyim0
Professor X One Trick :
is pervitin harmful?
2026-08-28 15:09:13
2
note_reckless
reckless savage :
thanks for the info bio
2026-08-08 09:00:04
17
emvchip
Nate Higgerson :
ascending in real time
2026-08-21 05:51:45
1
gabb3rhead
3bdi🪖 :
Neurogenesis does happen in adult hood but much slower compared to developing brains
2026-08-09 15:58:39
2
d4turatr1p
d4turatr1p :
I used lexapro and went manic
2026-08-18 22:15:03
1
femboycatboy
femboycatboy :
i tried few different SSRIs that psychiatrists gave me and they suck soooo damn much
2026-08-19 19:21:29
1
alexalex3123
Alex :
Neurogenesis appear not because of the drug itself. It doesn’t appear from the drug itself not in a drug called vortioxetine which is known to help the brain more than the other antidepressants. It appears because of the nervous system resting and learning new coping mechanisms. It is that simple
2026-08-09 08:54:58
2
mbeaz1
Beaz:) :
Bump
2026-08-08 05:47:20
2
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