@unusual_chris_jay: Ciprofloxacin strongly inhibits CYP1A2, the enzyme responsible for metabolizing tizanidine. This can cause a dramatic rise in tizanidine levels, leading to severe hypotension, bradycardia, dizziness, and excessive sedation. 👉 Key takeaway: Avoid this combination whenever possible and choose a safer alternative. #Pharmacy #MedicationSafety #DrugInteractions