@thediabetescollective: We know Leptin is a hormone secreted from fat cells, which regulate body weight because leptin's "job" is to send signals to your brain saying, "Hey, I'm full". But what if Leptin could be effective in more than just obesity treatment? That's why I sat down with world renowned Endocrinologist, and researcher, Dr. Irl Hirsch, to discuss Leptin and the treatment of hyperglycemia and diabetic ketoacidosis in Type 1 Diabetes. This is Dr. Hirsch's first public interview on his upcoming research plans, and I am honored to share his insights and plans for human clinical trials with you. It's important to understand the condition of type 1 diabetes doesn't simply mean deficiency of the hormone insulin. It includes Leptin as well. It's been proven that injecting Leptin into the brain has normalized glucose levels and eliminated ketones, but this has only been proven in animals thus far. It seems the medical community has spent the past 100+ years studying glucose metabolism via the liver, muscle, and adipose tissue. But, hasn't really understood how to study the brain, and that is what this is all about. Now the question is this: Can the human brain do a better job of controlling metabolism than other tissues? To learn more, you can read his publication on the "Unexpected role for the Brain in the pathogenesis of diabetic ketoacidosis" linked here: https://www.jci.org/articles/view/196357?utm_campaign=cover-page&utm_content=short_url&utm_medium=pdf&utm_source=content #t1d #Insulin #leptin

april_alive :

I’ll shave my head for you, put it in my brain

Curtis Doyle :

Awesome!

M :

Is there a study someone can volunteer. Me I am that someone.

mackiemarchandie :

How do they create T1D in mice when we don't know what causes T1D?

T1Vibes :

Great now I gotta inject stuff into my brain

e :

I LOVE HIM. A true diabetes hero!

Gloria Andrade :

Jane Wilson :

Take my money! How to get an appointment please 😂

Grownup T1Ds :

Wow! Eye opening and educational. Thank you for sharing this! It’s fascinating.

Your_Mom :

is it a one time thing????

Noelle 🌟 :

Sign me up for the trial study!!

Iota10 :

How does it create insulin without beta cells?

Jerzedoll :

can it be sublingual?

Sunofabotanist :

I need to be apart of the trial

wildthing :

How about a patch!

Valerie Navarro :

Super interesting, how do you do this as a routine, I can’t imagine it be affordable to most people

Justdrew :

But it won't cure type 2? what about Type 3?

DadoftheDesert :

This sounds amazing

LeisaLeisa :

Amylin too!

Shell 🐚 :

I hope there is some truth to this. Would love to hear more about it

radius6100 :

Thank you for sharing! I lost my pancreas in 2006 due to idiopathic pancreatitis. Harvested my own islets at the same time but became instantly diabetic due to low islet yield. Brittle diabetic now but low dose of insulin. Binders, receptors and signaling. 🤯

Cheyenne Hines-Agan :

I need this!!

Amanda Nicole :

How do I sign up to be in this trial?!🙏🏻

♡PriddyLacey♡ :

how do i sign up

Sara Baca :

sign me up!