@lipedemawarriorclinic: Could tirzepatide someday play a role in treating Lipedema itself — not just weight? A 2025 scientific review looked at how tirzepatide may interact with several processes involved in Lipedema, including inflammation, fibrosis, metabolism and adipose tissue dysfunction. The researchers found enough biological overlap to argue that tirzepatide deserves further study as a potential disease-modifying treatment. Important: this does not mean tirzepatide has been proven to treat Lipedema. Direct clinical evidence in Lipedema is still lacking, and more research is needed. But this is exactly why continuing to study Lipedema as more than simply “excess fat” matters. Want to learn more about Lipedema? Join our FREE Lipedema Warrior Clinic webinar on August 26. ✨ Register through the link in our bio. Study: Tirzepatide as a Potential Disease-Modifying Therapy in Lipedema www.mdpi.com/1422-0067/26/21/10741 #lipedema #lipedemaresearch #glp1 #lipedemafighter #womenshealth

Lipedema Warrior Clinic
Lipedema Warrior Clinic
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Region: US
Friday 21 August 2026 21:57:45 GMT
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kristinbuquoi
Kristin's Inspired by Sparkle :
Mounjaro for 4 years lost 125lbs. All the lipedema is still here and a lot loose skin. Now I can feel and see all of the pea to walnut size nodules that were left behind. It works for regular fat, but not for lipedema in my opinion.
2026-08-22 10:41:42
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user6234580436532
lala :
I been on zepbound for 2 1/2 years lost 70 lbs now I m not losing weight anymore I think it’s my legs have lipedema
2026-08-22 00:37:41
21
kathy_g03
KGo2468 :
I’ve been on tirzepitide since October 2024 and I have my life back. I’m in menopause so I take HRT.
2026-08-29 23:29:10
0
ghost627382
Ghost :
I learned this before the doctors were figuring it out 🤦🏻‍♀️
2026-08-29 20:32:15
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spokenheard89
The Coastal Midwest ™️ :
I am about to begin this drug, finally. I don’t have a diagnosis, but I know it’s happening. I’m in terrible pain as well, so I hope it helps. I miss my life.
2026-08-29 19:38:20
2
thetailypo
TheTailypo :
I have a diagnosis of lipedema and have been on tirzepatide for 2 years and for me it has been a miracle. I have some nodules but they are very small. The inflammation in my legs has gone down so much that I don't even look disproportionately pear-shaped anymore. My legs are no longer overly prone to bruising or overly sensitive compared to the rest of my body. My legs no longer become swollen and uncomfortable in the heat. The only downside is that I have some loose skin on my legs from having lost nearly 100 lb.
2026-08-23 02:12:51
18
18372528z31
Marino112 :
Weight loss will happen but the nodules are still there
2026-08-22 14:23:34
28
5five30thirty
fivethirty :
listen, I didn't have any diagnosis of lipodema but I did have high hereditary cholesterol and, I went through a probably 3-4 month plateau on a glp1, where the scale did not move. during that time, I had already lost about 65lbs... I would become aware of like, balls of fat, multiple, in areas like around my thighs, and specifically anywhere there was a crease, so legs meeting torso, etc. almost daily for whatever reason I would be itchy in a spot, and I would feel one of these balls that kind of varied in size and we're across many spots on my body... I would feel for it a few days later and it was gone. this went on for about 3 ish months, and now they're gone and I'm almost 90lbs down. there are a few spots where I still have some, that I believe likely are lipodema, but I feel like this glp1 is going to handle it so I'm not worried.
2026-08-23 04:41:16
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queen_morrigan
🩷💛🩵MORRIGAN🩷💛🩵 :
I want to be in a trial for this
2026-08-23 03:45:03
5
ornerywon
Ornery1 :
Why can’t I find a doctor to help me with this 😩
2026-08-25 17:16:34
4
d_anne_76
Anne :
I have both obesity and lipedema. Stage 3 with stage 1 lymphedema in one leg. Being on tirz has helped so much with my hips and legs. I have never seen my legs and hips respond like this to diet and exercise. I am on high protein, low carb diet and exercise as well as 3 mg tirz - I am hoping they study this
2026-08-21 22:59:15
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perryhancockphoto
Perry Hancock | Wedding Photo :
Can I schedule an appointment from Alabama??
2026-08-23 01:27:25
3
pinkpwnie
Kim 🧡🩵🧡🩵🧡🩵 :
I have stage 4 lipedema I was over 500lbs, I've lost 200lbs in the last two years.
2026-08-22 16:29:59
6
hermindseye
Sheila :
I wish the zepbound reduced my inflammation. For some reason it doesn’t and I also don’t lose normal fat even though I eat less.
2026-08-23 15:32:10
2
hinckley04
Jessica Hinckley :
Just got diagnosed today after 23 years of pain, heaviness etc. Lost 90lbs on Mounjaro now insurance won’t cover any of it and the pain is worse off Mounjaro than it was on it.
2026-08-26 04:26:30
1
alyssarnlove
RNloveNMmama :
I would love to be in a lipedema study so we can learn more
2026-08-22 18:54:57
10
kelly1111333
Spiritual warrior :
Do you see patients across the country?
2026-08-23 12:22:02
2
lauraperry8626
lauraperry8626 :
Citation, please?
2026-08-22 11:26:52
4
megabauman
meg :
I saw a ton of improvement in the inflammation in my legs and size went down but nodules seemed unaffected
2026-08-22 14:17:17
7
peach_ring_gummies
PeachRingGummies :
This post and comments are so helpful, because I brought up wanting surgery and my dr said that’s drastic and GLP1s could help. I hadn’t seen any studies or evidence of that.
2026-08-23 02:05:24
4
selizabeth.co
selizabeth.co :
But what happens when you stop the drug??
2026-08-27 19:29:23
4
nahnonoppiteynope
Nahnonoppiteynope 🆘🇺🇸😞 :
What about semaglutide?
2026-08-24 13:10:24
1
momadison
MicAddy :
Volunteer for the trial lost close to 90 lbs so now it's super obvious where I have lipedema!
2026-08-24 08:13:13
2
choosing95
✨Choosing Peace Everytime :
First, I like your delivery method. My question is can a GLP 3 have the same potential since it has the two components as Tirz?
2026-08-23 14:42:11
2
megasoreassrex
Megasoreassrex :
I started GLP-1 a few months ago. Never been formally diagnosed but definitely have lipedema.
2026-08-27 15:43:15
4
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