@erinrackham: Week 3– Guanfacine extended release (1 mg). The extended release leveled out within a few days for me and has been pretty good overall! Heart rate is still much lower and more stable than before, executive functioning is decent, and I don’t think it’s sedating me too badly now. #Guanfacine #HyperadrenergicPOTS #HyperPOTS
I’m struggling with the BP being too low. When did you notice it get better?
2026-08-30 00:41:48
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Inquilab Zindabad :
Yay! Congrats. Be aware that meds that impact cyp3A4 can impact guanfacine it's a very sensitive substrate.
2026-08-24 03:31:08
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Megan ☀️ :
my son takes a combo of guanfacine and stimulant and it's perfect for him.
2026-08-22 19:38:30
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Kiwixsenpai :
I was doing so well on it. my bp tanked by 20 points by the 4th day, which isnt normal. your posts helped my pharmocophobia and got me to try it in the first place though so thank you!
2026-08-29 06:33:26
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Addi 💌 :
I am on day five of ER and it’s fantastic!!! I only have had one baby adrenaline dump. But the nervous jitteriness is gone.
2026-08-23 02:21:38
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Solenya :
I’m day 9 and it has caused me a stupid amount of dizziness upon standing and walking. I’ve had to call in sick to work all week and my neuro thinks it’s due to me having a combo of hyper and neuro POTS. Guanfacine takes care of the hyper but then causes blood to pool more. As of today I’m trialing Midodrine stacked with it.
2026-08-30 21:46:05
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Accidentally Rural :
I’m on week 2 of 1mg ER and loving it! My heart rate seems to be lower and it has drastically calmed my nervous system. However, I am super tired during the day and my BP has been averaging 90/60. Hoping this is temporary. Thank you for originally posting about it. I never would’ve known about it if it wasn’t for your post.
2026-08-22 22:04:23
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Julez :
Are you still on a beta blocker if I may ask? If so what mg? I’m curious if you’re taking both meds together
2026-08-28 14:54:53
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amalija :
That stimulant, which one is it? I’ve been wanting to ask for a very tiny tiny dose one lol
2026-08-22 18:32:24
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Nanshe Groove :
Who can prescribe this? A normal doctor or psychiatrist?
2026-08-23 17:28:47
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wildseam :
Modafinil has changed my life.
2026-08-24 01:20:57
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Annmarie Pratt :
cardiologist starting point? I have my appointment November and trying to plan before
2026-08-24 05:47:18
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diyburbs4gh :
Very interested in this!
2026-08-22 16:56:46
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Whodat3210 :
Wow I want to try it now.
2026-08-23 03:36:12
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jlu3g :
I hated it. it made my arms numb and my hands tingle
2026-08-22 23:00:38
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pasttenseofdraw.mp3 :
I just started the immediate release! Are you taking it at night? Lowkey I don’t think me and my PCP ever discussed when to take it but I think night is the correct answer so that’s what I’ve been doing??? 😅
2026-08-23 07:00:52
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bleuch :
i was looking for this update!! glad its working so well for you!
2026-08-22 16:45:35
5
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