@doctor.painkiller: Two Neurologists Reveal Their Favorite Migraine Preventive Medications. Ask two neurologists for their favorite migraine preventive and apparently you’re not getting one answer. His answer: Vyepti. Mine: Nurtec for episodic, Qulipta for chronic. That doesn’t mean these are automatically the “best” medications for everyone — migraine prevention is highly individualized, and the right choice depends on attack frequency, other medical conditions, prior treatments, side effects, insurance coverage, and a lot more. As always this is for educational purposes only, not medical advice- talk to your doctor. We went much deeper into the current migraine treatment landscape — including CGRP medications, Botox, older preventives, and what’s changing — in our full conversation inside The Dark Room, which also includes my migraine courses, weekly live Q&As, expert conversations and the community. #migraine #migrainerelief #headache

Dr Painkiller: Migraine & Pain
Dr Painkiller: Migraine & Pain
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Region: US
Monday 24 August 2026 17:33:38 GMT
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yesiamrlyshort
Steph :
Qulipta changed my life. It's the best preventative I've ever used.
2026-08-26 02:23:35
0
mezimer
HD :
Qulipta side effects are awful
2026-08-24 19:25:18
10
julietmartin60
Jules :
Who can afford these? Qlipta is 655 dollars out of pocket monthly and Botox 888 dollars out of pocket for me. But dangerous drugs like gabapentin and others you can get cheaply. Please advocate for us doctors! Patients shouldn’t have to pay these outrageous costs!
2026-08-24 21:44:04
28
briebarbera
Brie Barbera :
Love Qulipta for chronic migraine 🙌🏻 Life changing.
2026-08-24 17:37:21
53
daniellejoy_33
Danielle Joy :
I love these conversations
2026-08-26 00:47:48
0
katiedan0323
Katie :
Love that ins denied injection meds but approves narcotics or others that do nothing. 30 yr chronic migraines here
2026-08-24 22:59:18
46
classicendeavor
Serious Moonlyte :
Aimovig was LIFE CHANGING and Qlipta has been a good substitute since my insurance wouldn’t cover it anymore.
2026-08-26 01:20:13
0
karlasworld02
Karla ♥️ :
Why does insurance give such a hard time to get Nurtec and it’s most drs choice 😭😭
2026-08-25 12:32:10
3
thetiredgingerbri
Bri Bri :
I had my first vyepti infusion last Wednesday, I also get botox and have nurtec for rescue...😅😅😅
2026-08-25 05:45:36
1
impactvelocity
Krystal :
is there an insurance that's better at approving migraine treatments?
2026-08-25 04:54:46
0
jmac12345
JMac :
Why does the person ‘fail’ and not the medication?
2026-08-24 19:14:34
10
katsyuga
🌺💠Katsyuga💠🌺 :
I tried Qulipta it did nothing it sucked.
2026-08-24 17:49:09
7
annefitz
Bulldog Mom :
I’m so glad you said this because I’m switching from Nurtec as a preventative to Qulipta and I’m nervous to take it 🙈
2026-08-24 17:53:26
11
riffy.rel
riffy_rel 🐢 :
Vyepti didn’t work for me 😔
2026-08-24 21:13:30
0
theunbreakableme
TheUnbreakableMe :
My neurologist has me on Qulipta for maintenance, and Nurtec for my abortive. I do Botox as well now. I went from 5 migraine days a week to 1! That combination was a lifesaver.
2026-08-24 19:21:21
6
user012432685
User :
Do either of you have familiarity with NDPH? I have been suffering for 18 months. Failed my first Vyepti infusion in March and worsened significantly for several weeks after
2026-08-24 18:11:52
2
louboutins_n_camo
louboutins_n_camo :
I love that he brought up insurance!
2026-08-24 21:38:49
5
mari_l23
Mari🌻 :
If insurance doesn’t want to cover Nurtec what would you recommend?
2026-08-24 21:21:59
0
dawnlabay
Dawn LaBay🏳️‍⚧️🏳️‍🌈💙 :
After trying what felt like 100 different meds, the combination of Botox and Vyepti broke the cycle of 420+ days of 5+ pain!
2026-08-24 22:54:07
6
bravaisfinejewelr
BravaisFineJewelry :
I just started vyepti at 100mg. I went from intractable for 1.5 years to 3 per week (24-72 hours each) with botox + aimovig then ajovy. Serious wear off effect each month. Migralief too. What dose do you see vyepti have most efficacy at?
2026-08-24 23:10:50
0
pedsnurseallie
Allie :
Qulipta changed my life. I don’t even care that it makes me sleepy, better than feeling like I’m having a stroke 5 days a week!
2026-08-25 01:14:51
4
tiredcatmom
Mollywo :
I’m on qulipta and loving it. Granted it makes me constipated but I’ve also lost like 20lbs on it
2026-08-24 21:17:56
1
skygazer1111
Skygazer111 :
can you take qulipta daily and nurtec as a rescue? I heard no because their same class and that would be like overdosing
2026-08-25 06:03:57
1
racheleyork
Rachel :
What if your migraines are really focused in your eyes and affect your vision (asking for a friend 👀)
2026-08-24 20:45:41
0
becxas
Parental Unit… Sometimes :
Are hormone migraines and different beast? Or do you use the same preventatives for hormone triggered?
2026-08-25 13:54:12
1
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