@drsermedmezher: “I Just Can’t Take Iron” #wait. Sources- Royal College of Pathologists PMID 37367984 @Bojo Iron deficiency anemia is commonly treated with oral supplementation, but high-dose regimens are frequently overprescribed in clinical practice. Healthcare providers historically recommended taking high-dose iron tablets two or three times daily under the assumption that more elemental iron translates to faster recovery. However, recent physiological research demonstrates that the human body cannot efficiently process these frequent, high-volume doses, often leading to unnecessary prescription loads that do not improve clinical outcomes. The key to iron absorption lies in the hormone hepcidin, which regulates iron entry into the bloodstream. A single dose of iron triggers a spike in hepcidin levels that lasts for up to 24 hours, temporarily blocking further iron absorption in the gut. Taking iron twice a day, or even on alternate days, prevents this continuous hepcidin elevation, resulting in higher fractional absorption rates and significantly fewer gastrointestinal side effects like nausea, constipation, and abdominal pain. #iron #women #eyebags

Dr Sermed Mezher MBChB MRes

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Friday 28 August 2026 21:04:11 GMT