@thepeptidedigest: “GLP-1s destroy your muscle.” 💀💪 You’ve probably heard that one. But newer research suggests the story may be a lot more nuanced than social media makes it sound. One reason? When studies report “lean mass loss,” that does NOT automatically mean the same amount of functional skeletal muscle disappeared. DEXA measurements categorize multiple forms of non-fat tissue as lean mass and can also be influenced by changes in water and glycogen during substantial weight loss. And here’s where things get interesting: In human research, researchers have observed decreases in measured muscle size while upper- and lower-body strength was maintained. That distinction matters. Lean mass ≠ skeletal muscle alone. Muscle size ≠ muscle function. Weight loss ≠ automatically becoming weak. Does that mean muscle preservation doesn’t matter on a GLP-1? Absolutely not. Protein intake, resistance training, adequate nutrition, rate of weight loss, and maintaining physical activity still matter enormously—especially during significant weight reduction. But saying “GLP-1s eat your muscle” oversimplifies what the data actually show. The better question isn’t: “Did lean mass decrease?” It’s: What tissue was actually lost—and what happened to strength and physical function? 🔬 Comment “CURIOUS” for the full deep dive into the data, biological pathways, and practical context. Educational and informational purposes only. This content is not medical advice. Medication, nutrition, and exercise decisions should be discussed with appropriately qualified healthcare professionals. #GLP1 #GLP1WeightLoss #WeightLoss #MuscleHealth #MusclePreservation

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Monday 31 August 2026 15:50:30 GMT