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@blingxsss:
Blingxsss
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Monday 31 August 2026 16:02:40 GMT
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A 2025 review proposes that the scattered symptoms of hEDS/HSD (joint instability, chronic pain, dysautonomia, even immune issues) may share one thread: the fascia. Imaging studies in hypermobile patients show the fascia is thickened, glides poorly, and is densely innervated with pain nerves, and the proposed loop is self-reinforcing (overactive cells lay down excess tissue, gliding drops, pain rises, repeat). Honest caveats: this is early and gets oversold. It’s a few small studies from largely one research group, the authors can see what’s happening but not why it starts, fascia is one piece of a complex picture (not the sole cause), and a structural finding doesn’t mean “fascia release” fixes it. Not a diagnosis or medical advice, and I’m not a doctor. Sources: Wang TJ, Stecco A, Hakim AJ, Schleip R. Fascial Pathophysiology in Hypermobility Spectrum Disorders and Hypermobile Ehlers–Danlos Syndrome. Int J Mol Sci. 2025;26(12):5587. DOI: 10.3390/ijms26125587. Wang TJ, Stecco A. Fascial thickness and stiffness in hypermobile Ehlers-Danlos syndrome. Am J Med Genet C. 2021;187(4):446-452. DOI: 10.1002/ajmg.c.31948. Wang TJ, et al. Change in gliding properties of the iliotibial tract in hEDS. J Ultrasound. 2023;26:809-813. DOI: 10.1007/s40477-023-00775-7. #heds #hypermobileehlersdanlossyndrome #hypermobility #ehlersdanlos
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