@drmaryclaire: Two hundred seventy-nine women, all already on estrogen therapy. 92.9% still had fatigue. 89.6% still had low libido. 88.9% still had memory problems. Researchers added transdermal testosterone without changing anyone's estrogen dose. At three months, 15 of 24 symptoms had significantly improved. Energy, musculoskeletal, mood, cognitive, genitourinary and endocrine symptom clusters all improved significantly. Neuropathic and cardiopulmonary symptoms did not move at all, which is actually reassuring, because a treatment that improves everything usually is not improving anything. Also worth saying plainly: this paper reported no safety data. No adverse events, no lipids, no hematocrit. It measured symptom scores only. Source: Hernandez BS, et al. J Sex Med. 2026;23(9):qdag116. Affiliations include Baylor College of Medicine and Newson Research, the research arm of a private UK menopause clinic. Education, not medical advice. Talk to your own clinician.
The 'Pause Life
Region: US
Wednesday 02 September 2026 20:01:17 GMT
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Grýla Gen ❌ :
I am on .075 estradiol patch 100 mg progesterone pill 2 mg testosterone cream a day and I do feel a lot better but still fighting, but I’m also in the end stages of perimenopause.
2026-09-12 12:18:30
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Suzanna_Ruelas :
What if the progesterone you have to take with the estrogen makes you a raging bull and your family is scared of you?
2026-09-12 21:15:24
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user1366261079359 :
Does it help with all over body pain
2026-09-11 12:40:23
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Ameri-Kiwi Mum 🇳🇿 :
as I run back to my doctor to ask her about transdermal testosterone
2026-09-12 04:30:07
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Sara :
This is all so very confusing. I wish there was clear guidance and how to determine which hormones you need and in which doses. I currently feel like a lab rat trying out various combinations. And things like fatigue and libido are so subjective, I can’t even tell for sure if they’re improving or not.
2026-09-02 20:24:07
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Urfavoritemama :
My gyno won’t prescribe Testosterone even though I told him I’m still experiencing some symptoms on HRT 😞
2026-09-02 23:11:50
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Tooth fairy :
I’ve been on HRT for a year. Testosterone for the last 2 months. Less muscle and joint pain and my crazy dry eyes are gone!!!!
2026-09-02 21:27:20
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Shelley Off The Wall :
Do you think a DHEA supplement is just as good for bringing up testosterone levels as the transdermal route?
2026-09-02 20:53:23
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🌼Monique🌼 :
I volunteer to be part of the clinical trial! Now if only our politicians respected us enough to fund this.
2026-09-02 20:05:09
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DanniGirl :
I’m on both and I’m still tired, still have low libido 😭
2026-09-02 22:25:15
6
Homefur :
My insurance will not cover it
2026-09-10 13:07:56
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gumbii5 :
I need the T, but all I get are bad side effects. No bennies. ☹️
2026-09-03 23:33:59
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LotionOnItsSkin :
I’m on both. It’s helps but now I spend a lot more on the waxing. If not, full goatee and handlebar mustache
2026-09-02 20:52:46
3
Carmen :
🗣️Testosterone also pulls from your ferritin storage so be careful all perimenopausal ladies that struggle with heavy periods and low iron 💯
2026-09-02 21:29:51
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Yasmin not Yasnice :
I want to do it but my hairrrr. I barely have the shedding under control.
2026-09-02 23:01:32
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Ashley :
I went to the doctor today to discuss a uterine ablation. When the topic of my medication came up, he spent 10 minutes talking about “there is no medical research proving HRT is effective.” I’m so sick of defending HRT with doctors. All I know was that I was in a really bad place for 5 years and now I feel more like myself.
2026-09-03 00:48:01
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Casey :
I was doing great until the shortage and the brand of my patch changed. Now I feel how I did before I started HRT. I use telehealth and they don’t prescribe T so I’m trying to find a dr now that can check that out for me.
2026-09-02 20:05:15
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🎼La la la la la.. :
I added a T gel last Nov. more energy, less brain fog, no mid day napping, and I have found the O again. My new OB tried to cancel my Rx because one blood test said my level was above “normal” by 20 points. I told her to test me again in three months. I didn’t stop and it was mid range for the next test. I will not go back to just est and pro.
2026-09-06 01:33:06
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Carolyn :
Anyone on testosterone cream and still experience brain fog and those brain issues ? Wondering how you guys might have dealt with that ?
2026-09-02 21:56:14
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dont.come.at.me.thirsty :
I'm on e, p and t and my only issue now is sleep disturbance. I woke up every 1.5-2 hours throughout the night
2026-09-02 21:12:02
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ARamMac :
I'm afraid if I go on T I'll be interested in mem again. no thanks 😂😂😂. I'd rather be tired.
2026-09-02 23:52:18
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Yo mama 330🧿🪬 :
Too bad the government funds more into male ED then childhood cancer or women’s health 😒
2026-09-05 14:55:02
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lizgallegos161 :
Been on testosterone for 4 months and haven’t seen a significant difference
2026-09-04 04:03:33
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IncRay :
Is transdermal better or IM? I saw a pharmacist that IM is better to avoid hair loss
2026-09-03 00:00:45
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OnnieJ :
How long does Testosterone usually take to kick in? It’s only been a week but i got nothing 😳
2026-09-02 21:55:25
2
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