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Friday 11 September 2026 14:14:44 GMT

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#Tcas #jknowledge #jsuper7 #tcas70 #viraltiktok

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For decades, scientists assumed the ovary simply shuts down after menopause — an emptied organ with nothing left to do. New research suggests it doesn't retire. It changes careers entirely. Researchers at Northwestern University's Feinberg School of Medicine, led by Francesca Duncan, studied mouse ovaries across three life stages: reproductively young, reproductively old, and fully post-reproductive. Rather than simply going quiet once egg release stopped, the ovaries underwent a complete cellular identity shift — infiltrated by T cells, macrophages, and multinucleated giant cells, transitioning from reproductive tissue into what researchers describe as an immune-like, inflammatory organ. The finding holds up in humans, too. Because studying healthy young ovaries isn't ethically feasible, Duncan's team instead compared ovaries removed from postmenopausal women aged 50 to 75, finding a shift in production across 177 different proteins in women over 70 compared to those in their 50s — with a marked increase in proteins tied to inflammation. Duncan admits she expected the opposite. Going in, she assumed a

For decades, scientists assumed the ovary simply shuts down after menopause — an emptied organ with nothing left to do. New research suggests it doesn't retire. It changes careers entirely. Researchers at Northwestern University's Feinberg School of Medicine, led by Francesca Duncan, studied mouse ovaries across three life stages: reproductively young, reproductively old, and fully post-reproductive. Rather than simply going quiet once egg release stopped, the ovaries underwent a complete cellular identity shift — infiltrated by T cells, macrophages, and multinucleated giant cells, transitioning from reproductive tissue into what researchers describe as an immune-like, inflammatory organ. The finding holds up in humans, too. Because studying healthy young ovaries isn't ethically feasible, Duncan's team instead compared ovaries removed from postmenopausal women aged 50 to 75, finding a shift in production across 177 different proteins in women over 70 compared to those in their 50s — with a marked increase in proteins tied to inflammation. Duncan admits she expected the opposite. Going in, she assumed a "nonfunctional" organ would look essentially the same across older age groups. Instead, the ovary kept molecularly transforming years after its reproductive job had ended — evidence that it wasn't dormant at all, just doing something entirely different. The implications reach beyond reproduction. Since women now spend a third or more of their lives in a post-reproductive state, and the ovary is already known to be one of the body's earliest-aging organs, researchers say this newly discovered immune activity could influence inflammation, disease risk, and aging throughout the entire body — not just within the ovary itself. source: Converse, A., Dipali, S.S., Schowe, I.P., et al. (2026). The post-reproductive ovary shifts from a reproductive to an immune-like organ. Molecular Human Reproduction, 32(2).

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We sing for love EVERYTHING, ALL AT ONCE, NEO 2026NCT.COM #NCTWISH #OdetoLove #NCTWISH_OdetoLove #NCT_10TH_ANNIVERSARY

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