@drmakkani: Nausea, reflux, constipation, and diarrhea are common GI side effects of GLP-1 medications like Ozempic, Wegovy, Mounjaro, and Zepbound. GLP-1s affect appetite, stomach emptying, intestinal movement, and signals between the gut and brain. That’s why GI symptoms can be especially noticeable when starting treatment or increasing the dose. Save this and follow for more GLP-1 education.

drmakkani | Internal Medicine
drmakkani | Internal Medicine
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Region: US
Tuesday 29 September 2026 00:18:14 GMT
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sandraloera16
Sandra Loera :
I get headaches don’t know why!😔
2026-11-01 22:15:03
0
staceymcgeekaras
Stacey McGee Karas :
I have a question if I’m having constipation with my glp 1 what would u say to take to help get back on track
2026-09-29 19:38:05
5
j.e.m.84
Jess_03 :
Hi doctor. I have a question. I did blood tests and my blood work came back great sugar wise, colesterol wise iron etc. I am 35.1 bmi over...obese...so i started miunjaro but it makes me feel like I need to faint everytime I take the shot within abiut 24 to 48hrs...I am only on 2.5mg ...any advise?
2026-09-29 15:12:18
2
user739411827
user5153974881063 :
i’ve been on 2.5 going into week 17 I have dropped nearly 30+ pounds had a little nausea in the beginning. Constipation is my big thing and I do everything I can. Thanks for your expertise.🥰
2026-09-29 17:23:44
22
renaek2001
Stacey Renae :
I take my first Monday and i am prone to constipation and I’m nervous so I’m hoping I have a good experience.
2026-09-29 15:00:32
3
debb_z
Debb_z :
I felt super weak got migraines, nausea but only when I ate “too much” maybe the first week. 2nd week I changed the injection site and no more symptoms. :)
2026-09-30 17:49:14
4
username61706170
Username :
The only time I’ve ever had diarrhoea on GLP1 was when I ate something that I shouldn’t have. I think I had a serving of mashed potato with mashed Swede/carrot. I.e. carbs. I rushed to the loo after that. It’s like your body only wants you to eat stuff that is good for it, and it can no longer tolerate the nonsense you put in it.
2026-09-30 15:10:31
5
shameerah.emamboc
Shameerah Emambocus :
hi doctor i almost reach my goal weight lost but am very weak and lost 27 kg in 6 months am afraid to regain the weigth back what supplement should i take please.
2026-09-30 04:42:11
3
gigiforfour
Gigi for six :
I had no symptoms for two years, lost 60 pounds and when I started maintenance and decreased to the lowest dose, I started feeling nauseous. Is that normal?
2026-09-30 03:10:43
3
sousankhouri
Sue :
I have been on it for a month i only dropped 6 pounds but I'm scared about what I'm hearing vision loss and all of that is that true?
2026-10-02 02:35:13
2
pippatinky
Pippa :
it stopped my ibs and Atypical facial pain. I suffered every day for 15 years. 5 years , no issues
2026-10-23 00:06:35
2
aimzeezoo
aimzeezooo :
Or 3/3 in me. So fun
2026-09-29 23:49:26
2
_cyn.x3
CYNDoesIt :
I got it all 😭
2026-09-29 16:44:39
3
lizcuddlebug
Liz Cuddlebug :
I have Barrett’s and no gall bladder and in menopause so it made me gain a lot of weight do you recommend it as my doctor said no
2026-10-03 09:26:30
1
chasinglights1
frasny V :
I get all 3 😭
2026-10-01 16:38:08
1
rossel_hair
HAIRSTYLIST/WIGMAKER BOTWE🇬🇭 :
Cause mine rather makes me feel hungry
2026-10-23 22:26:26
1
senorejz05
senorejz05 :
I always wondered
2026-09-29 01:48:55
3
phat.g
Phat G :
Why do so many doctors orecribe GLP-1's for patients who do not medically need it - people who want to lose 3-5kg , already skinny think Sharon and Kelly Osbourne, Ariana etc yet those that require it morbid obesity, high blood sugars, sleep apnea, inflammation
2026-10-08 04:35:11
0
taniamovingforward
Tania | Beginner Runner | :
This was a great explanation, my doctor just said it's common with no additional details. Thank you for this
2026-09-29 12:09:59
3
dozey23
dozey23 :
Thank you for this! I wanted to lose the weight I gained with an SSRI and perimenopause. I was told to do four weeks at lowest and then increase. I wish I would’ve known to just stay with low dose since I saw results. I ended up in the Er with horrific stomach cramps and couldn’t eat or drink for almost a week. I stopped of course and have been off for almost a month and half. Plan on going back on next week but, low dose and staying at.
2026-10-01 12:56:24
1
just_tess_o
Tess :
i cant take the fatigue im wiped out
2026-09-30 08:11:28
1
minuciosapo7
Minuciosapo🇪🇸🇭🇷 :
My IBS is better 😳 although some “safe” foods send me running now 😁
2026-09-30 17:05:01
1
dammy_remmy1
dammy_remmy :
Please what blood tests do I need to take before starting glp-1
2026-10-01 05:47:19
1
deliagarcia651
deliagarcia651 :
is brain fog normal on this medication?
2026-09-29 21:58:01
1
latin_queen02
Latin_Queen02🦋 :
2026-09-29 18:12:35
1
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