@nourishingapothecary: Why can anxiety suddenly feel so different in perimenopause? One piece of the puzzle is progesterone. Progesterone and its metabolites interact with the brain and nervous system, including GABA signalling, which has a calming effect. As ovulation becomes less consistent during perimenopause, progesterone exposure can become more variable too. For some women, that changing hormonal pattern can coincide with feeling more anxious, wired, unsettled or simply “not like myself”. This is why perimenopause isn’t only about hot flushes and changing periods. Hormonal changes can affect the brain and nervous system too. In Episode 5 of Inside the Apothecary, Toni, our Perimenopause Naturopath, joins us to unpack what is actually happening physiologically during this transition. Episode 5 is out now on Spotify, Apple Podcasts and YouTube. If you’re looking for individualised support through perimenopause, Toni consults at Nourishing Apothecary in Liverpool and via Zoom Australia wide. www.nourishingapothecary.com #perimenopause #progesterone #perimenopauseanxiety #womenshealth #nourishingapothecary

Jaime | Naturopath & Homeopath

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Monday 05 October 2026 05:00:35 GMT