@itsclairebell: this study estimated that MCAS is prevalent in 17% of the general population. yet it’s not often taught in medical school, and it’s rarely looked at in conjunction with mental health. I really think that needs to change. #mastcellactivationsyndrome #mcas #ehlersdanlossyndrome #histamine #MentalHealth

claire ! bell !
claire ! bell !
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Tuesday 06 October 2026 02:21:37 GMT
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contently.camille
Contently.Camille :
mcas, pmdd, audhd, ocd.... and im undiagnosed EDS. I think its all connected.
2026-10-06 10:03:18
147
bean4breakfast
bean4breakfast :
ALSO can be linked to uti feelings (ic/ painful bladder syndrome)
2026-10-06 18:13:54
13
m4r5hi
M4R5 :
all i know is that when i get worked up i vomit, when i’m scared i get hives, when my heart is broken my blood feels like poison . i just decided that my body is sensitive
2026-10-06 17:47:18
26
kayla_.joy1
Kayla_Joy :
I was literally just talking to my dad about how I think a lot of mental illness has todo with inflammation and mcas.
2026-10-06 18:13:02
2
xonova.exe
dj nova :
More histamine research is needed like yesterday
2026-10-06 02:29:56
62
aspenholliday
AspenHolliday🙃 :
waiiitttttt these are connected?!
2026-10-06 18:37:54
1
alexia._marie._
Ann Marie :
Never knew I had a histamine intolerance until last year and now my OCD has been at its worst AND now I see this vid? How odd loll but this is so interesting! I’ve always had the WORST time dealing with outbursts of emotions and SH, my feelings feel so physical that it genuinely feels like it could kill me, like I want to rip my skin off and pluck my eyes out. Absolutely awful and sooo hard to manage when I’m trying to have a polite disagreement & im not being heard :/ I thought I just had anger issues but ofc that has to stem from somewhere
2026-10-06 18:47:34
0
ecs123494
Elle S :
I’ve struggled with anxiety, depression, so, ocd, etc. after treating my mcas it’s near effortless in keeping my thoughts non dark. It took Cromolyn, Allegra, Pepcid, and microdose of zepbound. It’s a lot easier to keep your mood in check when your body isn’t on fire! Glad they’re connecting this
2026-10-06 09:22:38
66
meeks0753
sunlightandsorcery :
PLEASE everyone try Zyrtec. Truly a life changing medication
2026-10-06 18:45:36
1
melodysamm
melodysamm :
This is all very interesting. I have been taking Zyrtec all summer and honestly feel so much better. I have lots of the things you listed in the video. How do I go about getting tested for mast cell activation syndrome?
2026-10-06 05:13:29
10
chloswrldx
Chloë 🕷️ :
I have diagnosed MCAS and it 100% makes my mental health symptoms worse, especially PMDD. My theory is PMDD is just a MCAS flair + hormonal imbalance
2026-10-06 14:47:54
16
nnikkiinoodlehead
Nikki :
Yeah I’ve never had a doctor say anything to me about it. Just went my entire life thinking sensitive skin, allergic to every soap known to man, slapped with IBS. I am diagnosed with endometriosis and induced hypothyroidism
2026-10-06 16:12:58
4
cassiemarcum413
Casandra. :
BPD here, listening...
2026-10-06 18:09:10
2
rylandpark7928
Ryry79 :
I have MCAS and get so angry when I’m having flares… like my entire body is just so tense and uncomfortable I felt like I’m constantly on edge. Now that I have it managed I feel so much better
2026-10-06 12:37:50
20
ppeprincess
ppeprincess :
This is so important! I get rage during severe allergic/mast cell reactions and it needs to be recognized as the warning sign that it is and not a personal failing. You cannot CBT your way out of inflammatory chemicals
2026-10-06 06:56:57
77
melaniefixesmindsets
Mindset Melanie Business Coach :
I would put money on it all being hypermobility related- neurodivergence, histamine issues, and more are all from the fascia and how trauma manifests in the body/mind.
2026-10-06 14:45:48
4
heylauramae
Laura Mae 💪🖤 :
MCAS often goes hand in hand with mold toxicity. Not saying it’s the case for everyone but just leaving the comment incase anyone connects a dot…. When I have bad mold exposures I have major personality changes, rage, si, and more.
2026-10-06 10:30:45
2
gracieeb22
GB🌸 :
I’m a writer who specializes in trauma recovery, and cluster b disorders and I’ve been looking at this as well, and what I’ve learned about my own autoimmune diseases. I have many thoughts on this if you ever feel inclined to chat id be interested in exchanging what we’ve both found! Thanks for spreading some cool info!
2026-10-06 03:01:12
21
k8t.jo
Kate :
Yes! There are so many people in my life aside from myself that have MCAS (and/or EDS and POTS) the only thing we all have in common is neurodivergence. A couple currently have a BPD diagnosis but admit that are likely adhd or audhd also. It’s wild!
2026-10-06 03:21:30
3
thelightwon
TheLightWon :
How do you get diagnosed with a histamine disorder
2026-10-06 10:13:18
0
little.missmagic
little.missmagic :
I’m certain this is what I’m dealing with. BPD+MCAS+PCOS+hyperadrenergic POTS. The adrenal spikes from POTS worsen the MCAS spikes, & vice versa. Both of those things worsen PCOS hormone issues, which in turn just ramps up the POTS & MCAS flares. All together it affects my BPD & makes me so unstable & s**cidal. For a while, my BPD was much better & it was easier applying DBT in every day situations… then I went off a low histamine diet & started having flares again, & my mental health went out the window with it. I’ve been feeling so crazy lately bc I didn’t understand what could’ve set me back, & I thought I’d failed… so thank you, genuinely thank you so much! This came on my fyp at the perfect time when I needed answers so bad. Even though it’s depressing as hell to know its a vicious health cycle, it’s also so reassuring to have that clarity & realize I’m not just completely out of my mind every day.
2026-10-06 15:27:32
2
megm584
megm584 :
I’ve read this study. My treatment for MCAS, histamine and IBS-C has decreased and/or taken away my psychological symptoms. It’s been amazing and bizarre when you have lived with this your whole life. This is real and needs to be studied now. Thank you for sharing!![Starry hearts]
2026-10-06 15:51:34
1
cinnamontoastkunt0
cinnamontoastkunt :
I legitimately did have that EXACT issue. I was born with hereditary alpha tryptasemia and it manifested into MCAS in my late 20s and mastocytosis in my 30s
2026-10-06 14:42:05
1
fur_el1se
Für Elise :
I KNEW THIS WAS A THING I JUST COULDNT PROVE IT 😭 ugh I love tik tok cause it always points me to the most interesting case studies
2026-10-06 17:00:37
1
socialpainlab
Jesse they/them :
the SI part of that case series really stuck with me. i have MCAS and BPD too and noticed the same overlap you did. i've been deep in research on a theory that BPD comes from a dysregulated endorphin system, the body's own built-in comfort and pain relief. endorphin levels also rise and fall with estrogen, which might be part of why symptoms can shift with hormones. and there are trials that brought SI down fast by modulating the endorphin system (Yovell 2016, and a Stanford trial this year). i put it all together at bpd.fyi/research, but you're way better at explaining this stuff than i am. would you be up for trading notes?
2026-10-06 04:17:34
2
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