Chemist here. I have a genuine scientific question regarding this. Wouldn’t occlusion of the skin by a diaper cream containing approximately 40–50% paraffin increase hydration and permeability of the stratum corneum, potentially enhancing the penetration of tretinoin and azelaic acid into the skin? If so, couldn’t this also increase the risk of irritation, somewhat similarly to applying these active ingredients to damp skin, which can enhance their penetration? Thanks Abby!
2026-10-17 10:06:52
3
Solutionsnotbs :
How do you get it off in the morning? I tried Triple Paste 40% Zinc and took forever to wash off in the morning.
2026-10-07 02:54:05
2
user4937045185677 :
I can’t sleep with it. Too messy
2026-10-19 18:54:17
1
Top Katt :
I always worry since it locks it in it will intensify the actives and cause retinoid burn
2026-10-08 05:51:56
0
genxmoj :
Can you use tretinoin and azelaic acid together and if so, what is the benefit of that?
2026-10-17 21:26:21
0
Allie Callahan :
Any recs for this bestie im waiting on a second opinion derm. Happens anytime I use cleanser, goes 90% away with washing with just water. I’ve tried so many different kinds of cleanser and it still happens
2026-10-07 22:22:43
1
jj :
I had a non ablative fraxel laser last Nov and still have white mark scarring on forehead I have to reduce. Should i use axelaic acid w/my tretinoin. I onky have 10 percent ajd no change using it to date. Actual prequel and dr Murad scar cream has helped. Please assist- 60 and do not want to be dealing w this. Probably need another procedure. What is this whitish thick skin like scar layer? Thanks!
2026-10-28 10:09:05
0
Caroline :
I used zinc oxide overnight and now I have micro bumps and texture all over my skin☹️☹️☹️I have no clue what to do now
2026-10-07 03:22:51
0
RNKARA :
What about post CO2 laser?
2026-10-07 18:16:30
0
Yas :
I can’t find any nontoxic versions to use 😭
2026-10-08 01:25:17
0
MJJPrincess :
can it be used over retinol?
2026-10-14 16:32:20
0
Salih :
I thought it’s a bad idea to put an occlusive barrier on top of tretinoin
2026-10-07 12:35:09
0
factualreset :
how do you sleep with that shi on?
2026-10-08 11:44:16
0
Sunday Phillips, Founder & CEO :
How often can be used?
2026-10-07 19:38:50
0
Daniel. :
just take carrots people
2026-10-07 07:37:05
0
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