@dilaudiddaddy: Fentanyl: the drug everyone fears, and one of the most used drugs in the OR. What it actually is: Synthetic mu-opioid agonist, first made by Paul Janssen in 1960 💉 50–100x more potent than morphine, which is why we dose it in micrograms 💉 IV onset in 1–2 minutes, peak in about 5. Highly lipid-soluble, so it hits the brain fast. 💉 Short duration after a single dose because it redistributes out of the brain, not because it's eliminated. Infuse it long enough and it lingers. What we watch for: ⚠️ Respiratory depression. That's why someone trained in airway management never leaves your side. ⚠️ Chest wall rigidity ("wooden chest") with large, fast doses ⚠️ Bradycardia ⚠️ CYP3A4 interactions that can prolong its effect Why it's safe in the OR and deadly on the street: ✅ Pharmaceutical fentanyl is pure, dosed to the microgram, and given with monitors, oxygen, and naloxone at arm's reach ❌ Illicit fentanyl is pressed into pills of unknown strength, often mixed with other drugs, and taken alone Same molecule. Completely different context. #anesthesia #healthcare #nurse #medicine #surgery

Sunny | CAA
Sunny | CAA
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Friday 23 October 2026 15:51:58 GMT
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zahraofc1
ZahraOfc :
Why is morphine more stronger than fentanyl for me personally?
2026-10-23 17:10:23
4
bpenguin15
penguin15 :
got fentanyl when I got my tubes cut out..my doctor hooked me up! and I got a great script to take home of oxycodone..they make sure they take care of the woman in this town!♥️
2026-10-23 20:11:18
0
janet_ross62
Janet ross :
They gave me fentanyl after surgery and it put me out cold, I woke up in respiratory depression
2026-10-23 19:49:42
0
a29_84
Anni_84 :
Is Fentanyl and Oxycodone the same thing?🤔
2026-10-23 19:02:26
0
felix_elinmortal
Felix_ElInmortal :
Narcan is now OTC…? Narcan can be used as a precursor for countless Full Agonist Opioids. I feel a 4th Wave Opioid Crisis coming… 😬
2026-10-23 18:38:02
0
griffith.meg
Megan :
Can you do a video explaining pseudocholinesterase deficiency?
2026-10-23 18:50:30
0
error404usernotfound8755
Mr.K_on_elm_st :
I was on a drip of this stuff when I was on a ventilator in the icu after my accident.
2026-10-23 19:54:05
0
hypnoticjason
betterlifehypno :
I think I'll stick to gin & tonic.
2026-10-23 18:30:02
6
.leslie___._
Leślie :
I’ll pass
2026-10-23 16:35:43
4
im_metal_barbie25
im_metal_barbie25 :
That’s why I only slept for 30 minutes when they gave it to me 😂
2026-10-23 16:08:02
6
wimvanertvelde
WimVanErtvelde :
I had sufentanyl, it makes fentanyl look like an appetizer according to my anesthesiologist??
2026-10-23 16:35:40
11
andre82860
Andre 🇧🇻 ☆ andre82860 :
I like the way you explain things 👍
2026-10-23 17:50:58
0
neverending30
Understandable88 :
So serious question my mother overdosed what happens there
2026-10-23 18:40:36
0
anesthetic2k1
Mansoor Ahmad💉🩺 :
well explained sir ❤
2026-10-23 16:24:58
2
southernmurse
southern murse :
Oh man I don't know how people use this other than in medical setting. Was admitted to the ED with my gallbladder ready to explode and the doc elected to give me fentanyl for pain relief due to allergies. I told the triage nurse after 10 mins I'll take the damn pain back I was having my skin crawling so bad. No thanks
2026-10-23 17:37:10
2
kenken78682
kenny :
I had it for an endoscopy and it didn't work
2026-10-23 17:59:54
0
gopnikslav87
ROCOR Nektarios :
They gave this to my wife while she was in labor, it hit so fast, crazy though, I had no idea this stuff was in an epidural
2026-10-23 16:28:46
2
frobio_supplements
FroBio Labs :
Can you do a video on anesthesia with a history of Bleomycin? I’m about to have a colonoscopy and endoscopy and they are going to sedate me and I just finished bleomycin chemotherapy 2.5 months ago
2026-10-23 17:03:11
2
zachgriffiths85
zachgriffiths85 :
Can you or have you done one on TXA?
2026-10-23 16:31:34
1
jason.18012
goatmgxlxp5 :
Don't know why but when I've been in the hospital for pancreatitis Dilaudid seemed to work better for me.
2026-10-23 17:51:46
0
graysigraysi3
Graysi :
very useful content.💕
2026-10-23 16:04:40
1
armaan8318
Armaan :
what did they give me during my colonoscopy I used to have ulcerative collitis it was really bad by the time I had a colonoscopy they gave me gas and air it felt like I was just breathing in I nearly blacked out what did they use it completely got rid of all pain
2026-10-23 16:36:16
1
mamaw_90
@ mamaw :
Made me 🤢🤮
2026-10-23 16:05:43
1
howstupidarewe701
Uncle Joe :
when i was given that in the ER, my family choked. didn't realize it was actually used in medicine and not just something people die from
2026-10-23 17:43:01
3
lauriewachtmann
lauriewachtmann :
I had this for the first time for a STEMI and that's all I talked about for 3 days in the ICU. Give me more, I didnt give a shit bout nothing!! 😬
2026-10-23 18:40:32
1
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