@dilaudiddaddy: Fentanyl: the drug everyone fears, and one of the most used drugs in the OR. What it actually is: Synthetic mu-opioid agonist, first made by Paul Janssen in 1960 💉 50–100x more potent than morphine, which is why we dose it in micrograms 💉 IV onset in 1–2 minutes, peak in about 5. Highly lipid-soluble, so it hits the brain fast. 💉 Short duration after a single dose because it redistributes out of the brain, not because it's eliminated. Infuse it long enough and it lingers. What we watch for: ⚠️ Respiratory depression. That's why someone trained in airway management never leaves your side. ⚠️ Chest wall rigidity ("wooden chest") with large, fast doses ⚠️ Bradycardia ⚠️ CYP3A4 interactions that can prolong its effect Why it's safe in the OR and deadly on the street: ✅ Pharmaceutical fentanyl is pure, dosed to the microgram, and given with monitors, oxygen, and naloxone at arm's reach ❌ Illicit fentanyl is pressed into pills of unknown strength, often mixed with other drugs, and taken alone Same molecule. Completely different context. #anesthesia #healthcare #nurse #medicine #surgery
Sunny | CAA
Region: US
Friday 23 October 2026 15:51:58 GMT
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ZahraOfc :
Why is morphine more stronger than fentanyl for me personally?
2026-10-23 17:10:23
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penguin15 :
got fentanyl when I got my tubes cut out..my doctor hooked me up! and I got a great script to take home of oxycodone..they make sure they take care of the woman in this town!♥️
2026-10-23 20:11:18
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Janet ross :
They gave me fentanyl after surgery and it put me out cold, I woke up in respiratory depression
2026-10-23 19:49:42
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Anni_84 :
Is Fentanyl and Oxycodone the same thing?🤔
2026-10-23 19:02:26
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Felix_ElInmortal :
Narcan is now OTC…? Narcan can be used as a precursor for countless Full Agonist Opioids. I feel a 4th Wave Opioid Crisis coming… 😬
2026-10-23 18:38:02
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Megan :
Can you do a video explaining pseudocholinesterase deficiency?
2026-10-23 18:50:30
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Mr.K_on_elm_st :
I was on a drip of this stuff when I was on a ventilator in the icu after my accident.
2026-10-23 19:54:05
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betterlifehypno :
I think I'll stick to gin & tonic.
2026-10-23 18:30:02
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Leślie :
I’ll pass
2026-10-23 16:35:43
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im_metal_barbie25 :
That’s why I only slept for 30 minutes when they gave it to me 😂
2026-10-23 16:08:02
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WimVanErtvelde :
I had sufentanyl, it makes fentanyl look like an appetizer according to my anesthesiologist??
2026-10-23 16:35:40
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Andre 🇧🇻 ☆ andre82860 :
I like the way you explain things 👍
2026-10-23 17:50:58
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Understandable88 :
So serious question my mother overdosed what happens there
2026-10-23 18:40:36
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Mansoor Ahmad💉🩺 :
well explained sir ❤
2026-10-23 16:24:58
2
southern murse :
Oh man I don't know how people use this other than in medical setting. Was admitted to the ED with my gallbladder ready to explode and the doc elected to give me fentanyl for pain relief due to allergies. I told the triage nurse after 10 mins I'll take the damn pain back I was having my skin crawling so bad. No thanks
2026-10-23 17:37:10
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kenny :
I had it for an endoscopy and it didn't work
2026-10-23 17:59:54
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ROCOR Nektarios :
They gave this to my wife while she was in labor, it hit so fast, crazy though, I had no idea this stuff was in an epidural
2026-10-23 16:28:46
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FroBio Labs :
Can you do a video on anesthesia with a history of Bleomycin? I’m about to have a colonoscopy and endoscopy and they are going to sedate me and I just finished bleomycin chemotherapy 2.5 months ago
2026-10-23 17:03:11
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zachgriffiths85 :
Can you or have you done one on TXA?
2026-10-23 16:31:34
1
goatmgxlxp5 :
Don't know why but when I've been in the hospital for pancreatitis Dilaudid seemed to work better for me.
2026-10-23 17:51:46
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Graysi :
very useful content.💕
2026-10-23 16:04:40
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Armaan :
what did they give me during my colonoscopy I used to have ulcerative collitis it was really bad by the time I had a colonoscopy they gave me gas and air it felt like I was just breathing in I nearly blacked out what did they use it completely got rid of all pain
2026-10-23 16:36:16
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@ mamaw :
Made me 🤢🤮
2026-10-23 16:05:43
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Uncle Joe :
when i was given that in the ER, my family choked. didn't realize it was actually used in medicine and not just something people die from
2026-10-23 17:43:01
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lauriewachtmann :
I had this for the first time for a STEMI and that's all I talked about for 3 days in the ICU. Give me more, I didnt give a shit bout nothing!! 😬
2026-10-23 18:40:32
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