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Saturday 31 October 2026 02:22:14 GMT

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29 women with hEDS, 29 matched controls, and every protein researchers could measure in their blood. 35 came back different. 43% belonged to the complement system, 80% to immune, clotting or inflammation pathways, and almost none were collagen related. Complement is the part of your immune system that switches on during inflammation, so the immune system shows up in hEDS, not just connective tissue. The catch: one lab, a small all-female group, not replicated yet. Save this for the next time someone says hEDS is just your joints, tell me which immune symptoms you deal with, and send it to your hEDS friend. Not a doctor, and this isn't medical advice. Sources: Griggs M, et al. ImmunoHorizons. 2025;9(10):vlaf044. PMID 40972649 #heds #ehlersdanlos #hypermobility #hypermobileehlersdanlossyndrome

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