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@nurofficiel.com: #imam_ablaye_koita
nur officiel
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Region: CI
Saturday 31 October 2026 21:51:03 GMT
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Br > Cl >> F. step 2, fix a bad one: protonate the OH with a strong acid like HBr or H2SO4 so water leaves, or turn it into a tosylate with TsCl and pyridine, which keeps the carbon's configuration because the C-O bond is never touched. slide 5 is the 3 traps 🧐 an alcohol never leaves as HO- (NaCN plus an alcohol does nothing), fluoride is the worst halogen leaving group even though it is the most electronegative, and a good leaving group only makes SN1, SN2, E1 or E2 possible: the 1°, 2° or 3° carbon and the nucleophile or base still choose which one. slide 6 is today's quiz in the app 👀 which leaving group question always trips you up? 👇 #ochem #organicchemistry #sn2 #studytok #examprep" width="135" height="240">
your answer key says "SN2" and nothing about the leaving group? inkling explains why. search "inkling orgo" on the App Store or go to tryinkling.app good or bad leaving group, how to actually tell, for orgo 1 midterm 2 substitution and elimination: step 1, a good leaving group is a weak base that is stable on its own, the conjugate base of a strong acid. I-, Br-, Cl-, tosylate and mesylate and water (once it is protonated) leave well. HO-, RO-, NH2- and F- do not. going down the halogens it is I > Br > Cl >> F. step 2, fix a bad one: protonate the OH with a strong acid like HBr or H2SO4 so water leaves, or turn it into a tosylate with TsCl and pyridine, which keeps the carbon's configuration because the C-O bond is never touched. slide 5 is the 3 traps 🧐 an alcohol never leaves as HO- (NaCN plus an alcohol does nothing), fluoride is the worst halogen leaving group even though it is the most electronegative, and a good leaving group only makes SN1, SN2, E1 or E2 possible: the 1°, 2° or 3° carbon and the nucleophile or base still choose which one. slide 6 is today's quiz in the app 👀 which leaving group question always trips you up? 👇 #ochem #organicchemistry #sn2 #studytok #examprep
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