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@healthspanquest: it's crazy how it was scheduled to rain and then turned into a perfect night. Halloween was always one of my favorite holidays and then it seemed to fizzle after COVID, but now it's making a comeback even in a somewhat down economy. I'm seeing many putting in the effort to do Halloween and that seems really cool in these crazy times. I love that.

Coach Roger
Coach Roger
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Sunday 01 November 2026 02:11:10 GMT
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𝐂𝐚𝐧'𝐭 𝐭𝐚𝐤𝐞 𝐇𝐑𝐓, 𝐨𝐫 𝐝𝐨𝐧'𝐭 𝐰𝐚𝐧𝐭 𝐭𝐨? 𝐓𝐡𝐞𝐫𝐞'𝐬 𝐚 𝐧𝐨𝐧-𝐡𝐨𝐫𝐦𝐨𝐧𝐚𝐥 𝐡𝐨𝐭 𝐟𝐥𝐚𝐬𝐡 𝐩𝐢𝐥𝐥. 𝐇𝐞𝐫𝐞'𝐬 𝐭𝐡𝐞 𝐜𝐚𝐭𝐜𝐡 𝐧𝐨𝐛𝐨𝐝𝐲 𝐦𝐞𝐧𝐭𝐢𝐨𝐧𝐬. 🌡️ Hot flashes aren't only treatable with hormones. 💊 Fezolinetant (Veozah), FDA-approved in May 2023, works on the brain's temperature-control centre, not on hormones. 📊 SKYLIGHT 1 trial (Lancet 2023): women with 7+ moderate-to-severe hot flashes a day had about 2.5 FEWER per day than placebo at 12 weeks (45 mg). ⚠️ The catch: in December 2024 the FDA added a boxed warning for rare but serious liver injury. Blood tests are required before starting, monthly for the first 3 months, then at 6 and 9 months. 🚩 Stop and call your prescriber if you get unusual tiredness, nausea, itching, dark urine, or yellow eyes/skin. To be fair… placebo helps hot flashes a lot in trials too, so the extra benefit is real but modest. HRT remains the most effective treatment. 💛 Talk to your doctor about which option fits your health history. Don't start or stop anything alone. (My free Perimenopause Toolkit helps you prepare for your next appointment. Comment TOOLKIT and I'll send it to you 💛) If you've tried a non-hormonal option for hot flashes, what was your experience like? 📚 Sources: • Lederman S, Ottery FD, Cano A, et al. Fezolinetant for moderate-to-severe vasomotor symptoms associated with menopause (SKYLIGHT 1): a phase 3 randomised controlled study. The Lancet. 2023;401(10382):1091–1102. 527 women; vs placebo at week 12: −2.39/day (30 mg), −2.55/day (45 mg). • US FDA. FDA approves novel drug to treat moderate to severe hot flashes caused by menopause, May 12, 2023. • US FDA. Drug Safety Communication on rare serious liver injury with Veozah (fezolinetant), Sept 2024; Boxed Warning Dec 16, 2024. Liver tests before starting, monthly for 3 months, then at months 6 and 9. #menopause #perimenopause #hotflashes #nonhormonal #menopausesymptoms
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