@useinkling: DBU, t-BuOK, NaN₃, NaCN: the reagent tells you the mechanism before you draw anything 🖍️ there's a free sn2 or e2 lesson waiting in the app 📲 search "inkling orgo" on the App Store or go to tryinkling.app reagents for orgo 1 substitution and elimination: check if the carbon is 1°, 2° or 3° first. a strong small base like NaOEt gives E2 and the more substituted alkene on a 2° bromide. t-BuOK is bulky, so it mostly gives the less substituted alkene (Hofmann). DBU is a strong base but not bulky like t-BuOK, so it still mostly gives Zaitsev. NaN₃ and NaCN in DMSO are good nucleophiles and weak bases, so a 2° bromide does SN2 and the carbon inverts. ethanol with heat on a 3° bromide is mostly E1, with some SN1 ether. which reagent always throws you off? 👇 #ochem #organicchemistry #orgo1 #sn2 #studytok

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Tuesday 10 November 2026 17:30:00 GMT