@delanacommunity:

Yellow Matter
Yellow Matter
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Region: FR
Saturday 13 June 2026 20:14:57 GMT
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thoughtspaintedred3
Orange Matter :
Chat he sent me this
2026-06-13 20:19:24
29
alola18333
Blue Matter :
my bf is shitting at the moment
2026-06-13 20:24:56
23
thoughtspaintedred7
Red Matter :
I just need a boy😭😭
2026-06-13 20:26:10
6
adamb9631
𝓝𝓞*1𝓚𝓐𝓘𝓣𝓞.𝓕𝓐𝓝 :
I just cant she's 100 miles away
2026-06-14 19:18:31
6
urbashichaudhary6
kushal's mamu :
me to my baby
2026-07-22 14:28:47
0
gummybearmoe
Gummybear :
ooh to be loved 🥰he sent me this❤
2026-06-15 05:06:13
2
thoughtspaintedred2
Pink Matter :
I miss him so muchh
2026-06-13 20:17:57
7
thoughtspaintedred1
Grey Matter :
Should I send him?
2026-06-13 20:16:44
6
cathysanders50
cathysanders50 :
ok baby love me forever my baby ❤️❤️❤️
2026-06-16 13:22:02
0
aashish.ghale
Aashish Ghale :
@Monixa Khadka
2026-07-24 13:56:25
0
marsalann21
Marsalan :
@niza 😭
2026-07-25 22:03:40
1
.smokeend
zevxin🐈‍⬛ :
@⌇ 𝒮 ⌇ babiiaiaia
2026-06-14 17:15:09
1
psycho.675
PکYCнO 🕺🏻 :
@nieahh.priv🌺
2026-06-29 09:22:02
1
volvokung5
Volvokung5 :
@亗๒г๏ƙєภ1🥰🥰🥰🥰🥰🥰
2026-06-14 11:28:22
1
the_mistake_101
💫💫💫 :
@Daniel pretty please 🥹
2026-06-14 17:37:55
0
living_tochange
ᥫ᭡ ... ℐ🪽 :
@ℒ⋆.˚
2026-06-15 17:03:46
1
vandershuman
Vander :
@popppprivvvv
2026-06-14 14:28:16
0
_matheahagenpriv_
Jeg elsker tær :
@Joachim
2026-06-14 11:48:14
1
ln4d_of_dreams
Zia♡ :
@Ben Diamond
2026-06-22 22:25:15
1
forsakenfan2235
𓂃 ࣪ ִֶָ🪽࿐ никогда больше꥟˚꩜ :
@`` .𝘛𝘸𝘰 𝘛𝘪𝘮𝘦 .’ _꥟ ’’ ❤️
2026-06-14 08:28:21
1
kiraqq44
kiraqq44 :
@WalkerGHG
2026-06-14 13:38:50
1
nemesis._.sab
Sabrina Rita De Tull :
@alqssio ❤️
2026-06-14 17:28:21
1
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IBS, fibromyalgia, migraines, chronic pain conditions, and anxiety are typically treated by separate specialists with different diagnoses. Recent research is identifying mast cell activation as a shared underlying mechanism across all of them. A 2024 study by Van Remoortel et al. in Cell Reports Medicine reviewed mast cell modulation as a therapeutic target for IBS pain, showing mast cells directly drive pain-sensing nerve activation in the gut. Research by Theoharides and colleagues has documented thalamic mast cell involvement in fibromyalgia pain sensitization. A 2025 systematic review found IBS and fibromyalgia share mast cells, pro-inflammatory cytokines, and gut-brain disruption as common mechanisms. The migraine connection comes through CGRP release from mast cells, which is the same target as newer migraine medications. These conditions are now sometimes grouped together as nociplastic disorders. The mast cell connection across these conditions is well-supported in mechanistic research but mast cell stabilizers aren’t yet first-line treatments for IBS, fibromyalgia, or migraine. Treatment decisions should be made with a clinician who understands your specific symptoms. I’m not a doctor, just sharing research I find interesting. Sources: Van Remoortel et al. (2024). Cell Reports Medicine. DOI: 10.1016/j.xcrm.2024.101780 Theoharides et al. Mast Cells, Neuroinflammation and Pain in Fibromyalgia Syndrome. PMC6687840 2025 systematic review on FM-IBS shared mechanisms. PMC12701946 #mastcellactivationsyndrome #ibs #fibromyalgia #anxiety #migraine
IBS, fibromyalgia, migraines, chronic pain conditions, and anxiety are typically treated by separate specialists with different diagnoses. Recent research is identifying mast cell activation as a shared underlying mechanism across all of them. A 2024 study by Van Remoortel et al. in Cell Reports Medicine reviewed mast cell modulation as a therapeutic target for IBS pain, showing mast cells directly drive pain-sensing nerve activation in the gut. Research by Theoharides and colleagues has documented thalamic mast cell involvement in fibromyalgia pain sensitization. A 2025 systematic review found IBS and fibromyalgia share mast cells, pro-inflammatory cytokines, and gut-brain disruption as common mechanisms. The migraine connection comes through CGRP release from mast cells, which is the same target as newer migraine medications. These conditions are now sometimes grouped together as nociplastic disorders. The mast cell connection across these conditions is well-supported in mechanistic research but mast cell stabilizers aren’t yet first-line treatments for IBS, fibromyalgia, or migraine. Treatment decisions should be made with a clinician who understands your specific symptoms. I’m not a doctor, just sharing research I find interesting. Sources: Van Remoortel et al. (2024). Cell Reports Medicine. DOI: 10.1016/j.xcrm.2024.101780 Theoharides et al. Mast Cells, Neuroinflammation and Pain in Fibromyalgia Syndrome. PMC6687840 2025 systematic review on FM-IBS shared mechanisms. PMC12701946 #mastcellactivationsyndrome #ibs #fibromyalgia #anxiety #migraine

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