@candyposierosie: beside her career as an idol and being busy with schedules, she still continues her studies. keep going ella 🤍 she also said that her favorite subject were physics and literature ☺️ [ #MEOVV #ELLA #ELLAGROSS🦋 #THEBLACKLABEL ]

lusizhao
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Monday 31 August 2026 06:42:24 GMT
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dearlylovelyy
loviiiyyy🦋 :
di x ada yg terjemahin kl dia tetep di sekolah yg sama kya sblmnya tp skrg high school dn online class, dlu kan middle school oak christian, trs skrg jd high school oak christian (?)
2026-08-31 07:32:49
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GLP-1 receptor agonists are known for diabetes and weight, but a fast-growing body of research suggests they’re also broadly anti-inflammatory and immune-modulating. A 2025 systematic review described effects well beyond metabolism, including emerging interest in autoimmune and neurological conditions. The most direct evidence for MCAS so far is a single 2025 retrospective case series: 47 patients with treatment-resistant MCAS, 89% of whom showed clinical benefit, often within hours to days, across inflammatory, gastrointestinal, neurologic, and autonomic symptoms. Mechanistically, mast cells carry GLP-1 receptors, and these drugs dampen inflammatory pathways like TNF-alpha and NF-kB, which may explain it. The limitations matter and the hype skips them: this was retrospective, single-group, with NO control or placebo, and the authors themselves state that randomized controlled trials are needed before any of this is established. GLP-1 medications are serious prescription drugs with real side effects, real costs, and access issues, and they are NOT a proven or standard MCAS treatment. This is a promising research lead, not a recommendation. I’m not a doctor or scientist. Talk to a clinician who knows your history. Has anyone here been on a GLP-1 and noticed other symptoms change? Curious what you actually experienced. Sources: Afrin LB, Weinstock LB, Dempsey TT, Aschenbrenner K, Blitshteyn S, Schofield JR. Utility of GLP-1 receptor agonists in mast cell activation syndrome. Am J Med Sci. 2025;370(4):377-382. DOI: 10.1016/j.amjms.2025.07.006. Patel S, Niazi SK. Emerging Frontiers in GLP-1 Therapeutics: A Comprehensive Evidence Base. Pharmaceutics. 2025. DOI: 10.3390/pharmaceutics17081036. Alharbi SH. Anti-inflammatory role of GLP-1 receptor agonists and its clinical implications. Ther Adv Endocrinol Metab. 2024. DOI: 10.1177/20420188231222367. #mcas #mastcellactivationsyndrome #glp1 #semiglutide #autoimmune
GLP-1 receptor agonists are known for diabetes and weight, but a fast-growing body of research suggests they’re also broadly anti-inflammatory and immune-modulating. A 2025 systematic review described effects well beyond metabolism, including emerging interest in autoimmune and neurological conditions. The most direct evidence for MCAS so far is a single 2025 retrospective case series: 47 patients with treatment-resistant MCAS, 89% of whom showed clinical benefit, often within hours to days, across inflammatory, gastrointestinal, neurologic, and autonomic symptoms. Mechanistically, mast cells carry GLP-1 receptors, and these drugs dampen inflammatory pathways like TNF-alpha and NF-kB, which may explain it. The limitations matter and the hype skips them: this was retrospective, single-group, with NO control or placebo, and the authors themselves state that randomized controlled trials are needed before any of this is established. GLP-1 medications are serious prescription drugs with real side effects, real costs, and access issues, and they are NOT a proven or standard MCAS treatment. This is a promising research lead, not a recommendation. I’m not a doctor or scientist. Talk to a clinician who knows your history. Has anyone here been on a GLP-1 and noticed other symptoms change? Curious what you actually experienced. Sources: Afrin LB, Weinstock LB, Dempsey TT, Aschenbrenner K, Blitshteyn S, Schofield JR. Utility of GLP-1 receptor agonists in mast cell activation syndrome. Am J Med Sci. 2025;370(4):377-382. DOI: 10.1016/j.amjms.2025.07.006. Patel S, Niazi SK. Emerging Frontiers in GLP-1 Therapeutics: A Comprehensive Evidence Base. Pharmaceutics. 2025. DOI: 10.3390/pharmaceutics17081036. Alharbi SH. Anti-inflammatory role of GLP-1 receptor agonists and its clinical implications. Ther Adv Endocrinol Metab. 2024. DOI: 10.1177/20420188231222367. #mcas #mastcellactivationsyndrome #glp1 #semiglutide #autoimmune

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