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M Afzal Afzal
M Afzal Afzal
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Sunday 06 September 2026 15:58:59 GMT
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Replying to @louandherchildren People with a specific variant of the COMT (catechol-O-methyltransferase) gene may experience negative effects when taking quercetin due to the way their bodies process certain compounds. The COMT gene plays a crucial role in the breakdown of neurotransmitters like dopamine, norepinephrine, and epinephrine. It is involved in the methylation process, which adds a methyl group to these neurotransmitters, facilitating their breakdown and removal from the body. When people with low COMT activity take quercetin, a flavonoid commonly found in foods like onions, apples, and tea, they may experience negative side effects. ❗Quercetin has been shown to inhibit the COMT enzyme, which can exacerbate the already slow breakdown of neurotransmitters in those with low COMT activity. This results in a build-up of dopamine and other catecholamines in the brain, which can lead to symptoms like anxiety, agitation, restlessness, irritability, or even feelings of being overwhelmed. 👉🏻This can also be due to increasing histamine levels in the brain which also contribute to anxiety. Other things you can try to support histamine breakdown/ mast cell stabalization - Houttuynia Supreme - PEA - Palmitoylethanolamide - Baking soda in water 🙋🏼‍♀️ if you're looking for more support with histamine intolerance, you can book a consult as I am currently accepting new clients Let me know if you have more questions! This is not medical advice and is for educational purposes only. This information is not meant to treat, diagnose or prevent any medical condition. #histamineintolerance #urticaria #histamineflush #histaminehelp #histaminesensitivity #toxicmoldillness #moldtoxicity #anxietytips #candidaovergrowth #histaminesupport
Replying to @louandherchildren People with a specific variant of the COMT (catechol-O-methyltransferase) gene may experience negative effects when taking quercetin due to the way their bodies process certain compounds. The COMT gene plays a crucial role in the breakdown of neurotransmitters like dopamine, norepinephrine, and epinephrine. It is involved in the methylation process, which adds a methyl group to these neurotransmitters, facilitating their breakdown and removal from the body. When people with low COMT activity take quercetin, a flavonoid commonly found in foods like onions, apples, and tea, they may experience negative side effects. ❗Quercetin has been shown to inhibit the COMT enzyme, which can exacerbate the already slow breakdown of neurotransmitters in those with low COMT activity. This results in a build-up of dopamine and other catecholamines in the brain, which can lead to symptoms like anxiety, agitation, restlessness, irritability, or even feelings of being overwhelmed. 👉🏻This can also be due to increasing histamine levels in the brain which also contribute to anxiety. Other things you can try to support histamine breakdown/ mast cell stabalization - Houttuynia Supreme - PEA - Palmitoylethanolamide - Baking soda in water 🙋🏼‍♀️ if you're looking for more support with histamine intolerance, you can book a consult as I am currently accepting new clients Let me know if you have more questions! This is not medical advice and is for educational purposes only. This information is not meant to treat, diagnose or prevent any medical condition. #histamineintolerance #urticaria #histamineflush #histaminehelp #histaminesensitivity #toxicmoldillness #moldtoxicity #anxietytips #candidaovergrowth #histaminesupport


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